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- W3030893323 abstract "ObjectiveTo explore the effect of high blood lead level on semen quality and sex hormones levels in males.Methods156 male patients with high blood lead level were selected as the high blood lead group, and 180 healthy fertile men as the control group. Compared the main parameters of semen samples from the two groups using SQA-V Sperm Quality Analyzer, and the chemiluminescence was used to detect the serum prolactin (PRL), follicle-stimulating hormone (FSH), luteinizing hormone (LH), testosterone (T), and estradiol (E2).ResultsThe sperm density, motility, forward motility rate, and morphology rate of normal sperm in the high blood lead group were (54.16±18.89)×106 /ml, (42.47±15.72)%, (26.50±10.08)%, and (9.67±6.12)% respectively, which were all significantly lower than those in the control group [(68.33±27.81)×106 /ml, (57.90±19.87)%, (35.03±8.82)%, and (13.38±8.25)%]; serum FSH and LH levels in the high blood lead group were (11.57±5.19) mIU/ml and (9.76±4.05) mIU/ml, respectively, which were all significantly higher than those in the control group [(7.50±3.26) mIU/ml and (5.41±2.53) mIU/ml]; T level in the high blood lead group was (2.31±1.16) ng/ml, which was significantly lower than that in the control group [(6.97±2.28) ng/ml]; there were statistically significant differences between the two groups (all P<0.05).ConclusionHigh blood lead level will have a negative effect on male semen quality and serum sex hormones levels, resulting in male fertility decline.Key words: High blood lead; Semen quality; Sex hormones; Male infertility" @default.
- W3030893323 created "2020-06-05" @default.
- W3030893323 creator A5013038112 @default.
- W3030893323 date "2017-07-15" @default.
- W3030893323 modified "2023-09-28" @default.
- W3030893323 title "Analysis of semen quality and serum sex hormones levels in 156 male patients with high blood lead" @default.
- W3030893323 doi "https://doi.org/10.3760/cma.j.issn.1007-1245.2017.14.033" @default.
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