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- W3030923882 abstract "Septic shock is the most serious stage of sepsis and the main cause of the high mortality. So far, the scientists have paid more attentions on biomarkers for the early diagnosis and therapy monitoring of septic shock. As a kind of acute phase proteins, heparin-binding protein (HBP)has functions with increasing vascular permeability, sterilization, chemotaxis and regulating cell apoptosis. When the level of plasma HBP is high, it suggests that the patient has severe sepsis with edema and vascular collapse and can beapplied as a valuable biomarker for early diagnosis and therapy monitoring of septic shock. This review focuses on common inflammatory biomarkers for clinical application of sepsis, as well the structure and function of HBP and its clinical application of septic shock.(Chin J Lab Med, 2017, 40: 548-551)Key words: Shock, septic; Blood proteins; Biological markers" @default.
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- W3030923882 date "2017-07-11" @default.
- W3030923882 modified "2023-09-27" @default.
- W3030923882 title "The application and research progress of plasma heparin-binding protein in septic shock" @default.
- W3030923882 doi "https://doi.org/10.3760/cma.j.issn.1009-9158.2017.07.016" @default.
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