Matches in SemOpenAlex for { <https://semopenalex.org/work/W3030935511> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W3030935511 endingPage "677" @default.
- W3030935511 startingPage "674" @default.
- W3030935511 abstract "目的 探讨胃癌中caspase-3、survivin、CyclinD1及p27蛋白的表达及其与胃癌临床病理参数的关系.方法 采用免疫组织化学即用型二步法检测72例胃癌、54例正常胃黏膜组织中四种蛋白的表达.结果 caspase-3及p27蛋白在胃癌中的阳性表达明显低于正常胃黏膜(P＜0.01),survivin及CyclinD1在胃癌中的阳性表达明显高于正常胃黏膜(P＜0.01),caspase-3与组织分化程度和临床分期相关,survivin的表达与淋巴结转移、脏器转移和临床分期有关(P＜0.05),CyclinD1表达与组织分化程度相关,p27蛋白与组织分化程度、浸润深度、淋巴结转移、脏器转移、临床分期均相关.胃癌组织中caspase-3与survivin呈负相关,CyclinD1与survivin呈正相关,p27与CycfinD1也呈正相关.结论 survivin和CyclinD1蛋白的过表达,caspase-3和p27蛋白的表达缺失在胃癌的发生、发展中起着不同程度的作用.联合检测caspase-3,survivin,CyclinD1及p27蛋白的表达更能反映胃癌的生物学行为,优于单项检测。" @default.
- W3030935511 created "2020-06-05" @default.
- W3030935511 creator A5010611914 @default.
- W3030935511 creator A5033367533 @default.
- W3030935511 creator A5085788660 @default.
- W3030935511 date "2007-10-28" @default.
- W3030935511 modified "2023-09-25" @default.
- W3030935511 title "Expression of caspase-3 survivin CyclinD1 and p27 in gastric carcinoma and their significance" @default.
- W3030935511 doi "https://doi.org/10.3760/cma.j.issn.1006-9801.2007.10.009" @default.
- W3030935511 hasPublicationYear "2007" @default.
- W3030935511 type Work @default.
- W3030935511 sameAs 3030935511 @default.
- W3030935511 citedByCount "0" @default.
- W3030935511 crossrefType "journal-article" @default.
- W3030935511 hasAuthorship W3030935511A5010611914 @default.
- W3030935511 hasAuthorship W3030935511A5033367533 @default.
- W3030935511 hasAuthorship W3030935511A5085788660 @default.
- W3030935511 hasConcept C121608353 @default.
- W3030935511 hasConcept C126322002 @default.
- W3030935511 hasConcept C143998085 @default.
- W3030935511 hasConcept C190283241 @default.
- W3030935511 hasConcept C199360897 @default.
- W3030935511 hasConcept C2775975398 @default.
- W3030935511 hasConcept C2777546739 @default.
- W3030935511 hasConcept C41008148 @default.
- W3030935511 hasConcept C502942594 @default.
- W3030935511 hasConcept C54355233 @default.
- W3030935511 hasConcept C71924100 @default.
- W3030935511 hasConcept C86803240 @default.
- W3030935511 hasConcept C90559484 @default.
- W3030935511 hasConceptScore W3030935511C121608353 @default.
- W3030935511 hasConceptScore W3030935511C126322002 @default.
- W3030935511 hasConceptScore W3030935511C143998085 @default.
- W3030935511 hasConceptScore W3030935511C190283241 @default.
- W3030935511 hasConceptScore W3030935511C199360897 @default.
- W3030935511 hasConceptScore W3030935511C2775975398 @default.
- W3030935511 hasConceptScore W3030935511C2777546739 @default.
- W3030935511 hasConceptScore W3030935511C41008148 @default.
- W3030935511 hasConceptScore W3030935511C502942594 @default.
- W3030935511 hasConceptScore W3030935511C54355233 @default.
- W3030935511 hasConceptScore W3030935511C71924100 @default.
- W3030935511 hasConceptScore W3030935511C86803240 @default.
- W3030935511 hasConceptScore W3030935511C90559484 @default.
- W3030935511 hasIssue "10" @default.
- W3030935511 hasLocation W30309355111 @default.
- W3030935511 hasOpenAccess W3030935511 @default.
- W3030935511 hasPrimaryLocation W30309355111 @default.
- W3030935511 hasRelatedWork W1987645691 @default.
- W3030935511 hasRelatedWork W2000425293 @default.
- W3030935511 hasRelatedWork W2074504267 @default.
- W3030935511 hasRelatedWork W2076118454 @default.
- W3030935511 hasRelatedWork W2357447533 @default.
- W3030935511 hasRelatedWork W2359535677 @default.
- W3030935511 hasRelatedWork W2363192619 @default.
- W3030935511 hasRelatedWork W2380565237 @default.
- W3030935511 hasRelatedWork W2393753747 @default.
- W3030935511 hasRelatedWork W2409147322 @default.
- W3030935511 hasRelatedWork W3029183492 @default.
- W3030935511 hasRelatedWork W3029252014 @default.
- W3030935511 hasRelatedWork W3029498981 @default.
- W3030935511 hasRelatedWork W3032647440 @default.
- W3030935511 hasRelatedWork W3032890125 @default.
- W3030935511 hasRelatedWork W2565192028 @default.
- W3030935511 hasRelatedWork W3029904739 @default.
- W3030935511 hasRelatedWork W3030582346 @default.
- W3030935511 hasRelatedWork W3031154878 @default.
- W3030935511 hasRelatedWork W3031917147 @default.
- W3030935511 hasVolume "19" @default.
- W3030935511 isParatext "false" @default.
- W3030935511 isRetracted "false" @default.
- W3030935511 magId "3030935511" @default.
- W3030935511 workType "article" @default.