FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3030940842> ?p ?o ?g. }

• W3030940842 abstract "Abstract Background The purpose of this study is to analyze the influence of radiation therapy on survival in a historical cohort of 56 pediatric patients with head and neck rhabdomyosarcoma. Methods A historical cohort of 56 pediatric patients with head and neck rhabdomyosarcoma from June 1st, 2013 to June 30th, 2019 was chosen. Clinical data and follow up results were collected including all diagnosis, treatment and prognosis information. Overall survival (OS) and event free survival (EFS) as time-to-event distributions were estimated with Kaplan-Meier method, and univariate analysis was performed with log rank test to detect differences between groups. Multivariate analysis was performed to explore the risk factors for survival with Cox proportional hazard model. Results The media follow up time of all 56 patients was 31.8 months (range 3.5–74.6 months). There were 26 events during follow up, including 14 disease progressions and 12 relapses. The estimated 5-year OS of all patients was 69.9%, and the estimated 5-year EFS was 48.8%. Patients with radiation therapy as a component of the initial treatment plan had better 5-year OS and EFS compared with those without radiation therapy (OS 80.3% vs. 49.7%, p = 0.003 and EFS 63.9% vs. 21.9%, p < 0.001). In patients with events, those who received salvage radiation therapy had better 5-year OS compared with those who didn’t (OS 66.0% vs. 31.2%, p = 0.033). On multivariate analysis, tumor size > 5 cm and non-initial radiation therapy were independent risk factors for OS in all patients, non-initial radiation therapy was an independent risk factor for EFS in all patients, and tumor size > 5 cm was an independent risk factor for OS in patients with events. Conclusions Radiation therapy as a component of initial treatment can improve the OS and EFS in pediatric head and neck rhabdomyosarcoma patients by enhancing local control, and non-initial radiation therapy is an independent risk factor for OS and EFS. Salvage radiation therapy still can improve OS in patients with disease progression and relapse. Tumor size > 5 cm is an independent risk factor for OS in pediatric HNRMS patients with or without disease progression/relapse." @default.
• W3030940842 created "2020-06-05" @default.
• W3030940842 creator A5000147534 @default.
• W3030940842 creator A5012677271 @default.
• W3030940842 creator A5026711816 @default.
• W3030940842 creator A5043379516 @default.
• W3030940842 creator A5049151430 @default.
• W3030940842 creator A5078085004 @default.
• W3030940842 date "2020-05-29" @default.
• W3030940842 modified "2023-10-16" @default.
• W3030940842 title "Radiation therapy is an important factor to improve survival in pediatric patients with head and neck rhabdomyosarcoma by enhancing local control: a historical cohort study from a single center" @default.
• W3030940842 cites W1693048258 @default.
• W3030940842 cites W1914050662 @default.
• W3030940842 cites W1984504326 @default.
• W3030940842 cites W2001558906 @default.
• W3030940842 cites W2006994372 @default.
• W3030940842 cites W2077581316 @default.
• W3030940842 cites W2091470521 @default.
• W3030940842 cites W2094617809 @default.
• W3030940842 cites W2100034382 @default.
• W3030940842 cites W2101405991 @default.
• W3030940842 cites W2103879617 @default.
• W3030940842 cites W2109400179 @default.
• W3030940842 cites W2113173711 @default.
• W3030940842 cites W2139383226 @default.
• W3030940842 cites W2139874705 @default.
• W3030940842 cites W2142190381 @default.
• W3030940842 cites W2142896727 @default.
• W3030940842 cites W2148010242 @default.
• W3030940842 cites W2150648275 @default.
• W3030940842 cites W2163193120 @default.
• W3030940842 cites W2514075483 @default.
• W3030940842 cites W2618615945 @default.
• W3030940842 cites W2803823444 @default.
• W3030940842 cites W2809122047 @default.
• W3030940842 cites W2948756637 @default.
• W3030940842 cites W2951251179 @default.
• W3030940842 cites W2953324065 @default.
• W3030940842 cites W2970427574 @default.
• W3030940842 cites W2975416164 @default.
• W3030940842 cites W2990104134 @default.
• W3030940842 cites W2994952016 @default.
• W3030940842 cites W3005249069 @default.
• W3030940842 cites W4211210151 @default.
• W3030940842 doi "https://doi.org/10.1186/s12887-020-02165-y" @default.
• W3030940842 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7260775" @default.
• W3030940842 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32471472" @default.
• W3030940842 hasPublicationYear "2020" @default.
• W3030940842 type Work @default.
• W3030940842 sameAs 3030940842 @default.
• W3030940842 citedByCount "7" @default.
• W3030940842 countsByYear W30309408422022 @default.
• W3030940842 countsByYear W30309408422023 @default.
• W3030940842 crossrefType "journal-article" @default.
• W3030940842 hasAuthorship W3030940842A5000147534 @default.
• W3030940842 hasAuthorship W3030940842A5012677271 @default.
• W3030940842 hasAuthorship W3030940842A5026711816 @default.
• W3030940842 hasAuthorship W3030940842A5043379516 @default.
• W3030940842 hasAuthorship W3030940842A5049151430 @default.
• W3030940842 hasAuthorship W3030940842A5078085004 @default.
• W3030940842 hasBestOaLocation W30309408421 @default.
• W3030940842 hasConcept C10515644 @default.
• W3030940842 hasConcept C126322002 @default.
• W3030940842 hasConcept C141071460 @default.
• W3030940842 hasConcept C142724271 @default.
• W3030940842 hasConcept C143998085 @default.
• W3030940842 hasConcept C144301174 @default.
• W3030940842 hasConcept C207103383 @default.
• W3030940842 hasConcept C2778256501 @default.
• W3030940842 hasConcept C2780844630 @default.
• W3030940842 hasConcept C38180746 @default.
• W3030940842 hasConcept C44249647 @default.
• W3030940842 hasConcept C50382708 @default.
• W3030940842 hasConcept C509974204 @default.
• W3030940842 hasConcept C71924100 @default.
• W3030940842 hasConcept C72563966 @default.
• W3030940842 hasConceptScore W3030940842C10515644 @default.
• W3030940842 hasConceptScore W3030940842C126322002 @default.
• W3030940842 hasConceptScore W3030940842C141071460 @default.
• W3030940842 hasConceptScore W3030940842C142724271 @default.
• W3030940842 hasConceptScore W3030940842C143998085 @default.
• W3030940842 hasConceptScore W3030940842C144301174 @default.
• W3030940842 hasConceptScore W3030940842C207103383 @default.
• W3030940842 hasConceptScore W3030940842C2778256501 @default.
• W3030940842 hasConceptScore W3030940842C2780844630 @default.
• W3030940842 hasConceptScore W3030940842C38180746 @default.
• W3030940842 hasConceptScore W3030940842C44249647 @default.
• W3030940842 hasConceptScore W3030940842C50382708 @default.
• W3030940842 hasConceptScore W3030940842C509974204 @default.
• W3030940842 hasConceptScore W3030940842C71924100 @default.
• W3030940842 hasConceptScore W3030940842C72563966 @default.
• W3030940842 hasIssue "1" @default.
• W3030940842 hasLocation W30309408421 @default.
• W3030940842 hasLocation W30309408422 @default.
• W3030940842 hasLocation W30309408423 @default.
• W3030940842 hasLocation W30309408424 @default.
• W3030940842 hasOpenAccess W3030940842 @default.
• W3030940842 hasPrimaryLocation W30309408421 @default.
• W3030940842 hasRelatedWork W2013727445 @default.
• W3030940842 hasRelatedWork W2128245076 @default.

• next