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- W3030996966 abstract "ObjectiveTo investigate the clinical characteristics of polymyositis/dermatomyositis (PM/DM) complicated with venous thromboembolism (VTE).MethodsMedical records of patients with PM/DM at Peking Union Medical College Hospital from Jan 2000 to Oct 2014 were reviewed to identify VTE. The comparisons of various categorical clinical manifestations between groups were evaluated usingt - test andχ2 test.ResultsTwenty-three PM/DM patients developed VTE, which accounted for 1.86% of the 1 235 PM/DM patients hospitalized during the same period. Among these 23 patients (18 female and 5 male), 5 patients had PM and 18 patients had DM. With respect to the occurrence of VTE, no significant difference was found between DM and PM or between male and female. Their age was (57±7) years (range: 47-71 years old), significantly older than patients without thrombosis [(47±13) years,t=-3.191,P=0.001]. Twenty-one patients (75% , 21/28) developed VTE in the first year after the diagnosis of PM/DM. The incidence rate ratios (IRR) for DVT in PM/DM were 1.46% (18/1 235) and for PTE was 0.73% (9/1 235), in which 4 cases complicated with lower extremity DVT. Most patients exhibited active disease and high levels of D-Dimer during the emergence of VTE.ConclusionPatients with PM/DM have an increased risk of VTE, especially in older patients and at the early stage after the diagnosis of PM/DM, indicating that more attention should be paid to these patients in the clinic.Key words: Polymyositis; Dermatomyositis; Venous thromboembolism; Retrospective studies" @default.
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- W3030996966 date "2015-08-15" @default.
- W3030996966 modified "2023-09-28" @default.
- W3030996966 title "Clinical analysis of polymyositis/dermatomyositis complicated with venous thromboembolism: a report of 23 cases" @default.
- W3030996966 doi "https://doi.org/10.3760/cma.j.issn.1007-7480.2015.08.005" @default.
- W3030996966 hasPublicationYear "2015" @default.
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