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- W3031007908 abstract "ObjectiveTo explore the regional spontaneous activity changes in patients with trigeminal neuralgia (TN) using resting-state functional MRI.MethodsResting-state functional MRI datasets were acquired from 30 patients with TN, admitted to our hospital from July 2012 to December 2013, and 20 age, gender and education level matched healthy controls. The regional homogeneity (ReHo) method and independent-sample t-test were used to compare the brain activity differences between these two groups.ResultsDecreased ReHo values in the left temporal, left para-hippocampal, as well as increased ReHo values in the bilateral thalamus and left parietal lobe were noted in TN patients as compared with those in the healthy controls.ConclusionsThe abnormal spontaneous activity exists in TN patients, and these abnormal regions are mainly associated with the perception and processing of pain. In addition, spontaneous activity alternation might promote the exploration of mechanism of TN.Key words: Trigeminal neuralgia; Functional MRI; Regional homogeneity; Regional spontaneous activity" @default.
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- W3031007908 date "2015-11-15" @default.
- W3031007908 modified "2023-09-26" @default.
- W3031007908 title "Regional homogeneity changes in patients with trigeminal neuralgia" @default.
- W3031007908 doi "https://doi.org/10.3760/cma.j.issn.1671-8925.2015.11.012" @default.
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