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- W3031036000 abstract "Objective To investigate and confirm the value of minimal invasion of separation between specific subcutancous layers of rats.Methods Thirty-two male SD rats were randomized into four groups,group 1:normal incision plus separation beneath superficial fascia; group 2:normal incision plus subdermal separation; group 3:normal incision plus extended separation beneath superficial fascia ; group 4:extended incision plus separation beneath superficial fascia.Blood sampling was taken preopeatively,2 h,12 h,24 h and 48 h postoperatively.The increase of serum IL-6 and neutrophil elastase levels were compared between different groups.Results Compared with each other,the increase of serum IL-6 and NE levels in group 1 vs 3 and group 2 vs 4 was not different significantly (P value was 0.074,0.096 and 0.747,0.897,respectively).However,the increase of serum levels in group 1 vs 2,1 vs 4,3 vs 2 and 3 vs 4 was different significantly (P ＜ 0.01).Conclusion Operation of separating beneath superficial fascia plus small skin incision in rats conduces to relatively minimal invasion.Key words: Subcutaneous tissue ; Membranous layer; Inflammation ; Surgical procedures, minimal invasion" @default.
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- W3031036000 date "2013-03-15" @default.
- W3031036000 modified "2023-09-26" @default.
- W3031036000 title "Randomized controlled study of serum level of inflammatory mediator resulting from different skin incision and separation between different subcutaneous layers of rats" @default.
- W3031036000 doi "https://doi.org/10.3760/cma.j.issn.1673-4203.2013.03.008" @default.
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