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• W3031041438 abstract "Objective To investigate the correlation between the measurement methods of carotid- cerebral pulse wave velocity （ccPWV） and the traditional method of brachial-anlde pulse wave velocity CoaPWV）. Methods A total of 136 healthy volunteers were divided into a youth group （20-39 years）, a middle- aged group （40-59 years）, and an elderly group （more than 60 years） according to their ages. While detecting haPWV, transeranial Doppler ultrasound was used to sinmltaneously monitor the ipsilateral cotrmaon carotid artery and the terminal segment of internal carotid artery. The time differences of the beating points of their cardiac cycles and the distances of the skin surfaces between the 2 probes were measured and ccPWV was calculated. Results The systolic blood pressure, pulse pressure and mean arterial pressure in the elderly group were si~aificantly higher than those in the middle-aged group and the young group. The ccPWVs in the youth, middle-aged and elderly groups were 418 ±52 era/s, 489 ± 54 cm/s, and 599 ±58 cm/s, respectively. The elderly group was significantly faster than the middle-aged group （t = 7. 308, P 〈0. 001）, and the middle-aged group was significantly faster than the youth group （t = 6. 758, P 〈 0. 001）. A Pearson correlation analysis showed that cePWV was significantly positively associated with the age （r = 0. 847, P 〈 0. 001 ） and baPWV （r =0. 548, P 〈0. 001）. The multiple linear regression analysis showed that ccPWV was significantly positively associated with the age and diastolic blood pressure （partial correlation coefficients were 0. 742 and 0. 293 respectively, P 〈 0. 001 and 〈 0. 010 respectively）. Conclusions ccPWV is a new measurement method for eerebrovaascular stiffness, and it has a good correlation with the traditional measurement method.Key words: Blood Flow Velocity;  Pulsatile Flow;  Ultrasonography, Doppler, Trmls~maial;  Arteriosclerosis" @default.
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• W3031041438 date "2012-05-15" @default.
• W3031041438 modified "2023-09-23" @default.
• W3031041438 title "Carotid-cerebral pulse wave velocity and its influencing factors" @default.
• W3031041438 doi "https://doi.org/10.3760/cma.j.issn.1673-4165.2012.05.002" @default.
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