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- W3031052007 abstract "Objective To investigate the expression and clinical significance of β2 microglobin (β2-MG)protien and vascular endothelial growth factor (VEGF) protien in diffuse large B-cell lymphoma (DLBCL).Methods The expressions of VEGF protien and β2-MG protien were evaluated in 49 DLBCL patients which started the initial treatment by luminex suspension array.Results Among 49 DLBCL patients,expression of β2-MG protein was high in 37 cases and the expression of VEGF protein was high in 23 cases.The expression of VEGF protien and β2-MG protien were not related with gender,age,B symptoms,clinical stage and lactic acid (LDH).There was positive correlation between the high expression of β2-MG protien and chemotherapy (P =0.037).There was relevant trend between the higher expression of VEGF protien (P =0.067).Conclusion The expressions of VEGF protien and β2-MG protien are detected in DLBCL,both proteins may be the potencial markers of DLBCL and therapeutic targets for DLBCL.Key words: Lymphoma, large B-cell, diffuse; Vascular endothelial growth factors; β2 microglobulin" @default.
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- W3031052007 date "2013-10-28" @default.
- W3031052007 modified "2023-09-23" @default.
- W3031052007 title "Expression of β2 microglobin and vascular endothelial growth factors in diffuse large B-cell lymphoma and its clinical significance" @default.
- W3031052007 doi "https://doi.org/10.3760/cma.j.issn.1006-9801.2013.10.008" @default.
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