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- W3031058856 endingPage "e152" @default.
- W3031058856 startingPage "e143" @default.
- W3031058856 abstract "The aim of this systematic review was to describe the epidemiology, diagnostic criteria, differential diagnosis, treatment, prognostic factors, and treatment outcomes of secretory carcinoma.A comprehensive search of Lilacs, PubMed, Science Direct, and Web of Science databases was conducted to identify all case reports, letter to the editor, and histopathologic reclassifications regarding salivary gland secretory carcinoma published in English, Spanish, French, and Portuguese.The final analysis included 119 studies, which totaled 642 secretory carcinoma diagnoses, with 239 case reports and 403 diagnostic reclassifications, mostly in the United States. The age range was 5 to 87 years, and cases were predominantly in males (58.7%) and mostly affecting the parotid glands (73.7%). The disease usually presents as a slow-growing, painless mass. The main differential diagnosis is acinic cell carcinoma, and the tumor is usually treated with surgery. The prognosis is considered favorable, although there have been reports of local recurrences, distant metastases, and deaths.It is important that clinicians become aware of this salivary gland neoplasm and report clinical data, clinical course, management and long-term follow-up. There is an urgent need to conduct more clinical trials, especially on tropomyosin receptor kinase (TRK) inhibitors and other potential target therapy modalities." @default.
- W3031058856 created "2020-06-05" @default.
- W3031058856 creator A5006872222 @default.
- W3031058856 creator A5016901144 @default.
- W3031058856 creator A5017033996 @default.
- W3031058856 creator A5018199259 @default.
- W3031058856 creator A5022275813 @default.
- W3031058856 creator A5031354838 @default.
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- W3031058856 creator A5081718197 @default.
- W3031058856 creator A5083629632 @default.
- W3031058856 creator A5086517899 @default.
- W3031058856 date "2021-10-01" @default.
- W3031058856 modified "2023-10-10" @default.
- W3031058856 title "A systematic review of secretory carcinoma of the salivary gland: where are we?" @default.
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