Matches in SemOpenAlex for { <https://semopenalex.org/work/W3031081887> ?p ?o ?g. }
- W3031081887 abstract "Abstract Bioelectronic medicine is opening new perspectives for the treatment of some major chronic diseases through the physical modulation of autonomic nervous system activity. Being the main peripheral route for electrical signals between central nervous system and visceral organs, the vagus nerve (VN) is one of the most promising targets. Closed-loop neuromodulation would be crucial to increase effectiveness and reduce side effects, but it depends on the possibility of extracting useful physiological information from VN electrical activity, which is currently very limited. Here, we present a new decoding algorithm properly detecting different functional changes from VN signals. They were recorded using intraneural electrodes in anaesthetized pigs during cardiovascular and respiratory challenges mimicking increases in arterial blood pressure, tidal volume and respiratory rate. A novel decoding algorithm was developed combining discrete wavelet transformation, principal component analysis, and ensemble learning made of classification trees. It robustly achieved high accuracy levels in identifying different functional changes and discriminating among them. We also introduced a new index for the characterization of recording and decoding performance of neural interfaces. Finally, by combining an anatomically validated hybrid neural model and discrimination analysis, we provided new evidence suggesting a functional topographical organization of VN fascicles. This study represents an important step towards the comprehension of VN signaling, paving the way to the development of effective closed-loop bioelectronic systems." @default.
- W3031081887 created "2020-06-05" @default.
- W3031081887 creator A5009822156 @default.
- W3031081887 creator A5018269834 @default.
- W3031081887 creator A5034530138 @default.
- W3031081887 creator A5042680079 @default.
- W3031081887 creator A5049177848 @default.
- W3031081887 creator A5050784427 @default.
- W3031081887 creator A5061723893 @default.
- W3031081887 creator A5063156694 @default.
- W3031081887 creator A5064626414 @default.
- W3031081887 creator A5077236926 @default.
- W3031081887 creator A5079903363 @default.
- W3031081887 creator A5080060929 @default.
- W3031081887 creator A5087383226 @default.
- W3031081887 date "2020-06-01" @default.
- W3031081887 modified "2023-10-01" @default.
- W3031081887 title "Simultaneous decoding of cardiovascular and respiratory functional changes from pig intraneural vagus nerve signals" @default.
- W3031081887 cites W1978574256 @default.
- W3031081887 cites W1993694278 @default.
- W3031081887 cites W1999031782 @default.
- W3031081887 cites W2012853348 @default.
- W3031081887 cites W2028925130 @default.
- W3031081887 cites W2034300480 @default.
- W3031081887 cites W2046704078 @default.
- W3031081887 cites W2049176713 @default.
- W3031081887 cites W2097925212 @default.
- W3031081887 cites W2099454382 @default.
- W3031081887 cites W2108068079 @default.
- W3031081887 cites W2125081009 @default.
- W3031081887 cites W2129329622 @default.
- W3031081887 cites W2132984323 @default.
- W3031081887 cites W2136104363 @default.
- W3031081887 cites W2140285237 @default.
- W3031081887 cites W2148432454 @default.
- W3031081887 cites W2164012737 @default.
- W3031081887 cites W2166722928 @default.
- W3031081887 cites W2248997372 @default.
- W3031081887 cites W2285989687 @default.
- W3031081887 cites W2442539006 @default.
- W3031081887 cites W2469268362 @default.
- W3031081887 cites W2519728469 @default.
- W3031081887 cites W2718647198 @default.
- W3031081887 cites W2770384246 @default.
- W3031081887 cites W2787894218 @default.
- W3031081887 cites W2788012462 @default.
- W3031081887 cites W2789481298 @default.
- W3031081887 cites W2800689952 @default.
- W3031081887 cites W2802315660 @default.
- W3031081887 cites W2803358728 @default.
- W3031081887 cites W2901836189 @default.
- W3031081887 cites W2905170444 @default.
- W3031081887 cites W2911941880 @default.
- W3031081887 cites W2943870140 @default.
- W3031081887 cites W2969880795 @default.
- W3031081887 cites W3012733805 @default.
- W3031081887 cites W3091627004 @default.
- W3031081887 cites W3098938371 @default.
- W3031081887 cites W4243537131 @default.
- W3031081887 cites W4302067267 @default.
- W3031081887 doi "https://doi.org/10.1101/2020.06.01.127050" @default.
- W3031081887 hasPublicationYear "2020" @default.
- W3031081887 type Work @default.
- W3031081887 sameAs 3031081887 @default.
- W3031081887 citedByCount "3" @default.
- W3031081887 countsByYear W30310818872021 @default.
- W3031081887 crossrefType "posted-content" @default.
- W3031081887 hasAuthorship W3031081887A5009822156 @default.
- W3031081887 hasAuthorship W3031081887A5018269834 @default.
- W3031081887 hasAuthorship W3031081887A5034530138 @default.
- W3031081887 hasAuthorship W3031081887A5042680079 @default.
- W3031081887 hasAuthorship W3031081887A5049177848 @default.
- W3031081887 hasAuthorship W3031081887A5050784427 @default.
- W3031081887 hasAuthorship W3031081887A5061723893 @default.
- W3031081887 hasAuthorship W3031081887A5063156694 @default.
- W3031081887 hasAuthorship W3031081887A5064626414 @default.
- W3031081887 hasAuthorship W3031081887A5077236926 @default.
- W3031081887 hasAuthorship W3031081887A5079903363 @default.
- W3031081887 hasAuthorship W3031081887A5080060929 @default.
- W3031081887 hasAuthorship W3031081887A5087383226 @default.
- W3031081887 hasBestOaLocation W30310818871 @default.
- W3031081887 hasConcept C11413529 @default.
- W3031081887 hasConcept C126322002 @default.
- W3031081887 hasConcept C154945302 @default.
- W3031081887 hasConcept C169760540 @default.
- W3031081887 hasConcept C24998067 @default.
- W3031081887 hasConcept C2777372248 @default.
- W3031081887 hasConcept C2777953023 @default.
- W3031081887 hasConcept C2780375056 @default.
- W3031081887 hasConcept C2781404750 @default.
- W3031081887 hasConcept C41008148 @default.
- W3031081887 hasConcept C529278444 @default.
- W3031081887 hasConcept C534529494 @default.
- W3031081887 hasConcept C57273362 @default.
- W3031081887 hasConcept C71924100 @default.
- W3031081887 hasConcept C84393581 @default.
- W3031081887 hasConcept C86803240 @default.
- W3031081887 hasConceptScore W3031081887C11413529 @default.
- W3031081887 hasConceptScore W3031081887C126322002 @default.
- W3031081887 hasConceptScore W3031081887C154945302 @default.