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• W3031105565 abstract "Objective To evaluate the motor-related activation of cortical regions in patients who suffered hemiparesis after subcortical infarction in acute phase and relationship between functional near infrared spectroscopy (fNIRS) signal and Fugl-Meyer score.Methods We employed fNIRS to evaluate cortical activation with affected hand movement in 8 patients after subcortical infarction causing mild to moderate left hemiparesis in early phase(≤ 14 days).Eight right-handed normal subjects without stroke history served as controls.Block design of hand grasp task was used.The activated channels were compared between patients and controls.Correlative analysis was performed between fNIRS signal and Fugl-Meyer score in patients.Results The activated cortices in patients were larger than that of controls.Controls activated the right primary sensorimotor cortex (CH14、8、15、20 和 21,P ＜ 0.01) during left hand grasp task.However,patients showed extended activation not only in the right motor cortex(CH15、8、2、22、3、20、16、14、27、35、41、1、10 和 36,P ＜ 0.01) but also in the left motor cortex including prefrontal cortex (CH5 和 CH37,P ＜ 0.01)during the same task.No statistical correlation was found between fNIRS signal and Fugl-Meyer score.Conclusions Cortical reorganization can be detected early after subcortical infarction by using fNIRS.The result of this study demonstrated that fNIRS was suitable for studying poststroke alterations in cortical response to motor stimulation.Key words: Subcortical infarction;  Functional near infrared spectroscopy;  Cortical functional reorganization" @default.
• W3031105565 created "2020-06-05" @default.
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• W3031105565 date "2013-08-28" @default.
• W3031105565 modified "2023-09-22" @default.
• W3031105565 title "Functional near infrared spectroscopy finding of spontanous recovery of motor function after subcortical infarction" @default.
• W3031105565 doi "https://doi.org/10.3760/cma.j.issn.1001-2346.2013.08.017" @default.
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