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- W3031123004 abstract "Objective To observe the expression of paraoxonase-1 (PON1) between type 2 diabetic and normal age-related cataract.Methods The lenses were obtained from 36 cases of type 2 diabetic patients and 50 age-related cataract patients during the surgery.The ELISA was used to detect expression of PON1 and enzyme activity assay was selected to analysis activity of PON1.Results The enzymatic activity of PON1 in type 2 diabetic age-related cataract was lower than normal age-related cataract (t =4.38,P ＜0.01),however,the amount of PON1 in two groups had no difference (t =0.2305,P =0.82).Conclusions Lower enzymatic activity of PON1 is detected in type 2 diabetic age-related cataract,which may be explained for the changed structure.In-depth study should be carried out in the future.Key words: Paraoxonase-1; Lens; Cataract; Diabetes" @default.
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- W3031123004 date "2013-01-10" @default.
- W3031123004 modified "2023-09-23" @default.
- W3031123004 title "Difference of paraoxonase-1 in lens between type 2 diabetic and normal age-related cataract" @default.
- W3031123004 doi "https://doi.org/10.3760/cma.j.issn.1006-4443.2013.01.008" @default.
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