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- W3031126059 abstract "Introduction: Quinoxalines show diversified applications in the field of medicinal chemistry. Materials and Methods: Therefore, we have designed a highly efficient, environmentally benign and one-pot protocol for the synthesis of 2-phenylquinoxaline from the reaction of Acetophenone, N-bromosuccinimide and 1,2-phenylenediamine under ultrasound irradiation in glycerol-water. Results and Discussion: We observed that, although the reaction efficiently completed in all of these solvents, the use of glycerol-water with different ratios gives consistently higher yields (89–94%) and decreases reaction times. Conclusion: The main advantages of this protocol are that it is a green method, avoids the use of toxic catalysts and volatile organic medium and the product is obtained with excellent yield." @default.
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- W3031126059 date "2020-09-25" @default.
- W3031126059 modified "2023-09-25" @default.
- W3031126059 title "Highly Efficient Ultrasound Promoted Synthesis of 2-phenylquinoxaline in Glycerol- Water" @default.
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- W3031126059 doi "https://doi.org/10.2174/1570179417666200529121602" @default.
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