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- W3031144350 abstract "Objective To explore the phenomenon of neural apoptosis after chronic compressive spinal cord injury. Methods A newly designed chronic progressive compressive spin al cord injury model of rat was adopted in this study. Forty-five Wister rats w ere divided into mild, moderate, and severe group according to the compressive degree of the spinal cord. The Feulgen stain and TUNEL were use d to investigate the apoptosis and its characteristics in different kinds of neu ral cells. Results Apoptosis index in moderate injury group was the hi ghest. Apoptotic cells largely located in ventral, lateral and dorsal column of the white matter. Most of them were oligodendrocytes. Positive neuron occasi onally presented in laminae Ⅲ~Ⅸ part of the sections. Most of them located in dorsal gray horn. Conclusions Apoptosis is an important event in secondary pat hophysiological process of chronic progressive compressive spinal cord injury. A poptosis is one of the reasons for neural cell death. The apoptosis of oligodend rocytos may contribute to myelin sheath disruption of white matter. [" @default.
- W3031144350 created "2020-06-05" @default.
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- W3031144350 date "2001-01-01" @default.
- W3031144350 modified "2023-09-25" @default.
- W3031144350 title "Experimental study of apoptosis in chronic compressive injury of the spinal cord" @default.
- W3031144350 hasPublicationYear "2001" @default.
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