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- W3031193250 abstract "目的 探讨四逆汤对肾性高血压主要靶器官的保护作用机制.方法 健康大鼠24只,随机分为正常组、对照组和治疗组各8只,根据双侧肾动脉夹闭法建立肾性高血压动物模型,给予四逆汤灌胃治疗,用RBP-2大鼠血压计测量鼠尾血压,HE染色和免疫组织化学方法分别检测心脏、肾脏、脑等靶器官的组织病理学变化和超氧化物歧化酶(SOD)的表达.结果 四逆汤治疗组动物血压显著低于对照组(P＜0.05),主要靶器官心脏、肾脏和脑组织内SOD表达水平显著高于对照组(P＜0.01).结论 四逆汤对肾性高血压具有调节作用,通过抗氧化机制对高血压靶器官起一定的保护作用。" @default.
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- W3031193250 date "2007-11-30" @default.
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- W3031193250 title "Protecting function of Decoction for Treating Yang Exhaustion (Si Ni Tang) on Target Organ of Hypertension" @default.
- W3031193250 doi "https://doi.org/10.3760/cma.j.issn.1673-4246.2007.06.011" @default.
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