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- W3031193744 abstract "Acute respiratory distress syndrome (ARDS) is common disease in the clinic which induce a high mortality of 40%. Unbalanced inflammation plays a key role in pathophysiological mechanisms of ARDS development. T helper 17(Th17) and regulatory T (Treg) cells are a pair of CD4+ T cell subsets with opposite functions. Th17 cells can mediate inflammatory response while Treg cells can inhibit T cell-mediated inflammation and maintain immune tolerance. The imbalance of these two T cell subsets are exist in ARDS, but the mechanism and understanding of Th17/Treg imbalance remains lack of consensus. In this review, we will focus on the recent findings related to role of Th17/Treg imbalance in immunity regulating in ARDS.Key words: Acute respiratory distress syndrome; Immune response; T helper 17; Regulatory T cells" @default.
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- W3031193744 date "2019-02-28" @default.
- W3031193744 modified "2023-09-27" @default.
- W3031193744 title "Advancements in the research on balance of T helper 17 and regulatory T cells in immunity of acute respiratory distress syndrome" @default.
- W3031193744 doi "https://doi.org/10.3877/cma.j.issn.2096-1537.2019.01.012" @default.
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