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- W3031212111 abstract "目的 通过对不同检测系统血清酶测定进行方法比对和偏倚评估,探讨不同检测系统间血清酶测定结果的可比性,为不同实验室检验结果的互认和实验室认可提供实验数据. 方法参考NCCLS的EP9-A2文件,以日立7170生化分析仪、罗氏原装试剂、C.f.a.s校准品和质控品组成的检测系统(已通过ISO/IEC 17025标准认可)为目标检测系统(比较方法),检测系统1~4为实验方法,用病人新鲜血清对丙氨酸氨基转移酶(ALT)、碱性磷酸酶(ALP)、天冬氨酸氨基转移酶(AST)、乳酸脱氢酶(LDH)和肌酸激酶(CK)进行检测,计算实验方法(Y)和比较方法(X)之间的相对偏差(% SE),以美国临床实验室修正法规(CLIA'88)规定的室间质量评价允许误差范围的1/2为标准,判断不同检测系统测定结果的可比性. 结果除检测系统4的ALT结果、检测系统1 ALP测定的高值(>150 U/L)、检测系统3和检测系统4的AST结果与比较方法的系统误差不能被接受外,其余项目测定结果的系统误差临床可以接受. 结论当用两个以上的检测系统检测同一检验项目时,应进行方法比对和偏倚评估,判断其临床可接受性能,以保证检验结果的可比性。" @default.
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- W3031212111 date "2006-04-26" @default.
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- W3031212111 title "The comparative study and the bias estimation on the result of serum enzymes with different biochemical detecting system" @default.
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