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- W3031230237 abstract "目的 分析婴幼儿巨细胞病毒感染的临床特征和更昔洛韦治疗的临床疗效.方法所有48例病人于入院初、诱导和维持治疗后进行巨细胞病毒抗体检测、肝脏功能测定和血常规检查,确诊后予更昔洛韦诱导和维持治疗.结果婴幼儿巨细胞病毒感染临床表现多种多样,以肝脏、肺脏、消化道和血液系统损害为主,20.8%合并先天性畸形;经对症和更昔洛韦抗病毒治疗,39例黄疸消退(39/43, 90.7%),17例(17/32,51.1%)肝脏肿大,11例(11/29,31.9%)脾脏肿大回缩至正常,83.3%的患者CMV-IgM转阴,ALT、AST、γ-GT、T-Bili和D-Bili明显降低,差异非常显著(P＜0.01),骨髓抑制不明显,各阶段白细胞、红细胞和血小板改变不明显,差异无显著性(P＞0.05).结论婴幼儿巨细胞病毒感染,可侵犯多个脏器,临床表现多种多样,更昔洛韦治疗有效,副作用小。" @default.
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- W3031230237 date "2004-07-10" @default.
- W3031230237 modified "2023-09-25" @default.
- W3031230237 title "婴幼儿巨细胞病毒感染48例临床特征及疗效分析" @default.
- W3031230237 doi "https://doi.org/10.3760/cma.j.issn.1008-1372.2004.07.039" @default.
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