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- W3031231618 abstract "ObjectiveTo compare preoperative enteral nutrition (EN) , rapid bowel preparation (RBP) and traditional bowel preparation (TBP) on postoperative short- and long-term outcomes in colorectal cancer (CRC) patients.MethodsOne hundred and eighty-three CRC patients underwent radical excision from March 2011 to February 2013. They were randomly divided into EN group, RBP group and TBP group, and outcomes in the three groups were assessed.ResultsPatients’tolerance in EN group was better than the other two groups (95.1%, 83.6% and 52.5%, P<0.01) . The adverse events rate of the three groups, including abdominal pain/abdominal distension and nausea/vomiting, was 6.6%, 14.8% and 23.6%, respectively (P<0.01) . The rate of edema of bowel wall in EN group was lower than that in RBP group, which was lower than in TBP group (P<0.01) . The diarrhea rate of three groups was 6.6%, 11.5% and 24.6%, respectively (P=0.013) . The risk of biochemical disorders of preoperative anesthesia, 1, 3 and 5 days after surgery in EN group was lower than other two groups, and TBP group had the greatest risk of biochemical disorders. Postoperative complications, including wound infection, abdominal infection and anastomotic leakage, were 9.8%, 11.5% and 14.8%, respectively (P=0.679) . The frequency of tumor cells in peritoneal/intestinal cavity tumor cells of the three groups were 3.3%, 13.1% and 18.0% (P=0.039) . The 3-year local recurrence (LR) and/or distant metastasis (DM) in three groups were 13.1%, 18.0% and 14.8%, respectively (P=0.744) . Intestinal function recovery time and hospital stay differences among groups were statistically different (P=0.043, 0.037, respectively) .ConclusionsEN, RBP and TBP regimens are safe and effective in preoperative bowel preparation for colorectal cancer. In patients with EN, the degree of tolerance, intestinal clearance, postoperative complications were comparable to RBP and TBP. Edema of bowel wall in EN regimen was lower. Although the EN regimen can effectively reduce the incidence of peritoneal/intestinal cavity tumor cells, it can not improve the long-term prognosis of colorectal cancer.Key words: Colorectal neoplasms; Bowel preparation; Prognosis" @default.
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- W3031231618 date "2015-12-01" @default.
- W3031231618 modified "2023-09-24" @default.
- W3031231618 title "Analysis of short- and long-term outcomes in colorectal cancer patients with different bowel preparations after radical surgery: a single-center randomized controlled trial" @default.
- W3031231618 doi "https://doi.org/10.3877/cma.j.issn.1674-0793.2015.06.009" @default.
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