Matches in SemOpenAlex for { <https://semopenalex.org/work/W3031256610> ?p ?o ?g. }
Showing items 1 to 57 of
57
with 100 items per page.
- W3031256610 endingPage "230" @default.
- W3031256610 startingPage "225" @default.
- W3031256610 abstract "Hypertension is a major risk factor for cardiovascular morbidity and mortality. Optimum adherence to medication is still a perplexing matter for hypertensive patients in Nigeria and serum markers use as predictor for medication adherence has not been conclusive.To define the level of antihypertensive medication adherence, its possible correlation with serum uric acid (SUA) levels and other predictors of antihypertensive medication adherence among Nigerian patients.Patients were recruited from the University Teaching Hospital Cardiology Clinic. Blood was drawn for SUA levels. Validated 8-item MMAS-8 was administered to hypertensives to measure adherence, and correlations analysed between SUA levels and the MMAS-8 score, with SPSS-23. SUA is defined as elevated in men with concentrations of =430µmols/l, normal range 200-430µmols/l, and =360µmol/l in women, normal range140-360µmol/l. Linear regression analysis of the predictors of antihypertensive medication adherence was done. A statistical p value of <0.05 was considered significant.The total number and mean age of the cases were 271 and 60.8±12.3years respectively. MMAS-8 revealed that about half of the hypertensives (131 cases, 48.3%) had low adherence (MMAS-8 score 4), 81 cases (29.5%) had medium adherence (MMAS-8 score 2) while 59 cases (22.1%) showed high adherence (MMAS-8 score 0). Bivariate Correlation between SUA levels in hypertensives and antihypertensive medication adherence was of moderate degree and significant (r=0.396, p<0.001) suggesting that SUA levels increased with increasing non-adherence to antihypertensive medications. This correlation remained significant after adjusting for singular confounding variables like age (r=0.371 fair relationship, p=<0.001), DM (r=0.382 fair relationship, p<0.001); blood pressure (BP) duration and class r=0.356, 0.306, fair relationship p<0.001 respectively). The correlation between SUA levels and adherence to antihypertensive medications was weakened (r=0.209, p<0.001) after adjusting for combined confounding variables. Linear regression revealed that SUA levels is a predictor of antihypertensive medication adherence.Antihypertensive medication adherence was unsatisfactory, elevated SUA levels correlated with low antihypertensive adherence, and this correlation was influenced by several singular and combined confounding variables in our patient population. Hence SUA levels can be a predictor and a marker of antihypertensive medication adherence." @default.
- W3031256610 created "2020-06-05" @default.
- W3031256610 creator A5020632670 @default.
- W3031256610 creator A5033444973 @default.
- W3031256610 creator A5043210899 @default.
- W3031256610 creator A5082961205 @default.
- W3031256610 creator A5083832300 @default.
- W3031256610 creator A5086819231 @default.
- W3031256610 date "2020-06-02" @default.
- W3031256610 modified "2023-09-27" @default.
- W3031256610 title "Serum Uric Acid Predicts Antihypertensive Medication Adherence in Nigeria: A Hospital Based Study." @default.
- W3031256610 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32476115" @default.
- W3031256610 hasPublicationYear "2020" @default.
- W3031256610 type Work @default.
- W3031256610 sameAs 3031256610 @default.
- W3031256610 citedByCount "1" @default.
- W3031256610 countsByYear W30312566102023 @default.
- W3031256610 crossrefType "journal-article" @default.
- W3031256610 hasAuthorship W3031256610A5020632670 @default.
- W3031256610 hasAuthorship W3031256610A5033444973 @default.
- W3031256610 hasAuthorship W3031256610A5043210899 @default.
- W3031256610 hasAuthorship W3031256610A5082961205 @default.
- W3031256610 hasAuthorship W3031256610A5083832300 @default.
- W3031256610 hasAuthorship W3031256610A5086819231 @default.
- W3031256610 hasConcept C126322002 @default.
- W3031256610 hasConcept C2779881121 @default.
- W3031256610 hasConcept C2780192228 @default.
- W3031256610 hasConcept C3018553135 @default.
- W3031256610 hasConcept C71924100 @default.
- W3031256610 hasConcept C84393581 @default.
- W3031256610 hasConceptScore W3031256610C126322002 @default.
- W3031256610 hasConceptScore W3031256610C2779881121 @default.
- W3031256610 hasConceptScore W3031256610C2780192228 @default.
- W3031256610 hasConceptScore W3031256610C3018553135 @default.
- W3031256610 hasConceptScore W3031256610C71924100 @default.
- W3031256610 hasConceptScore W3031256610C84393581 @default.
- W3031256610 hasIssue "3" @default.
- W3031256610 hasLocation W30312566101 @default.
- W3031256610 hasOpenAccess W3031256610 @default.
- W3031256610 hasPrimaryLocation W30312566101 @default.
- W3031256610 hasRelatedWork W1965503220 @default.
- W3031256610 hasRelatedWork W2016171650 @default.
- W3031256610 hasRelatedWork W2171668659 @default.
- W3031256610 hasRelatedWork W2298385859 @default.
- W3031256610 hasRelatedWork W2364140508 @default.
- W3031256610 hasRelatedWork W2400321745 @default.
- W3031256610 hasRelatedWork W2504479046 @default.
- W3031256610 hasRelatedWork W2582387971 @default.
- W3031256610 hasRelatedWork W2786752171 @default.
- W3031256610 hasRelatedWork W4250469152 @default.
- W3031256610 hasVolume "37" @default.
- W3031256610 isParatext "false" @default.
- W3031256610 isRetracted "false" @default.
- W3031256610 magId "3031256610" @default.
- W3031256610 workType "article" @default.