FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3031311700> ?p ?o ?g. }

• W3031311700 abstract "Abstract This paper presents a new cell culture platform enabling label-free surface-enhanced Raman spectroscopy (SERS) analysis of biological samples. The platform integrates a multilayered metal-insulator-metal nanolaminated SERS substrate and polydimethylsiloxane (PDMS) multiwells for the simultaneous analysis of cultured cells. Multiple cell lines, including breast normal and cancer cells and prostate cancer cells, were used to validate the applicability of this unique platform. The cell lines were cultured in different wells. The Raman spectra of over 100 cells from each cell line were collected and analyzed after 12 h of introducing the cells to the assay. The unique Raman spectra of each cell line yielded biomarkers for identifying cancerous and normal cells. A kernel-based machine learning algorithm was used to extract the high-dimensional variables from the Raman spectra. Specifically, the nonnegative garrote on a kernel machine classifier is a hybrid approach with a mixed nonparametric model that considers the nonlinear relationships between the higher-dimension variables. The breast cancer cell lines and normal breast epithelial cells were distinguished with an accuracy close to 90%. The prediction rate between breast cancer cells and prostate cancer cells reached 94%. Four blind test groups were used to evaluate the prediction power of the SERS spectra. The peak intensities at the selected Raman shifts of the testing groups were selected and compared with the training groups used in the machine learning algorithm. The blind testing groups were correctly predicted 100% of the time, demonstrating the applicability of the multiwell SERS array for analyzing cell populations for cancer research." @default.
• W3031311700 created "2020-06-05" @default.
• W3031311700 creator A5039859789 @default.
• W3031311700 creator A5042741541 @default.
• W3031311700 creator A5052698723 @default.
• W3031311700 creator A5052996577 @default.
• W3031311700 creator A5055276776 @default.
• W3031311700 creator A5081300060 @default.
• W3031311700 creator A5084173892 @default.
• W3031311700 date "2020-06-01" @default.
• W3031311700 modified "2023-10-16" @default.
• W3031311700 title "Scalable nanolaminated SERS multiwell cell culture assay" @default.
• W3031311700 cites W1555009525 @default.
• W3031311700 cites W1602880342 @default.
• W3031311700 cites W1963638325 @default.
• W3031311700 cites W1971873096 @default.
• W3031311700 cites W1973724012 @default.
• W3031311700 cites W1989792962 @default.
• W3031311700 cites W1989941207 @default.
• W3031311700 cites W1992450009 @default.
• W3031311700 cites W2000430101 @default.
• W3031311700 cites W2001255811 @default.
• W3031311700 cites W2002685197 @default.
• W3031311700 cites W2006882472 @default.
• W3031311700 cites W2019916133 @default.
• W3031311700 cites W2021185388 @default.
• W3031311700 cites W2034551256 @default.
• W3031311700 cites W2042086388 @default.
• W3031311700 cites W2042704577 @default.
• W3031311700 cites W2055439074 @default.
• W3031311700 cites W2068774288 @default.
• W3031311700 cites W2072451938 @default.
• W3031311700 cites W2072553327 @default.
• W3031311700 cites W2080966248 @default.
• W3031311700 cites W2090031361 @default.
• W3031311700 cites W2110489045 @default.
• W3031311700 cites W2115797520 @default.
• W3031311700 cites W2124259769 @default.
• W3031311700 cites W2127617643 @default.
• W3031311700 cites W2157840751 @default.
• W3031311700 cites W2166190367 @default.
• W3031311700 cites W2257061815 @default.
• W3031311700 cites W2261541998 @default.
• W3031311700 cites W2317178824 @default.
• W3031311700 cites W2328915352 @default.
• W3031311700 cites W2342845453 @default.
• W3031311700 cites W2408424991 @default.
• W3031311700 cites W2566542095 @default.
• W3031311700 cites W2584523080 @default.
• W3031311700 cites W2606487236 @default.
• W3031311700 cites W2618880080 @default.
• W3031311700 cites W2626913208 @default.
• W3031311700 cites W2664191082 @default.
• W3031311700 cites W2797445881 @default.
• W3031311700 cites W2808859550 @default.
• W3031311700 cites W2879237511 @default.
• W3031311700 cites W2914374702 @default.
• W3031311700 cites W2974028224 @default.
• W3031311700 cites W4210705898 @default.
• W3031311700 cites W4234368842 @default.
• W3031311700 cites W971616299 @default.
• W3031311700 doi "https://doi.org/10.1038/s41378-020-0145-3" @default.
• W3031311700 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8433130" @default.
• W3031311700 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34567659" @default.
• W3031311700 hasPublicationYear "2020" @default.
• W3031311700 type Work @default.
• W3031311700 sameAs 3031311700 @default.
• W3031311700 citedByCount "14" @default.
• W3031311700 countsByYear W30313117002020 @default.
• W3031311700 countsByYear W30313117002021 @default.
• W3031311700 countsByYear W30313117002022 @default.
• W3031311700 countsByYear W30313117002023 @default.
• W3031311700 crossrefType "journal-article" @default.
• W3031311700 hasAuthorship W3031311700A5039859789 @default.
• W3031311700 hasAuthorship W3031311700A5042741541 @default.
• W3031311700 hasAuthorship W3031311700A5052698723 @default.
• W3031311700 hasAuthorship W3031311700A5052996577 @default.
• W3031311700 hasAuthorship W3031311700A5055276776 @default.
• W3031311700 hasAuthorship W3031311700A5081300060 @default.
• W3031311700 hasAuthorship W3031311700A5084173892 @default.
• W3031311700 hasBestOaLocation W30313117001 @default.
• W3031311700 hasConcept C119857082 @default.
• W3031311700 hasConcept C120665830 @default.
• W3031311700 hasConcept C121332964 @default.
• W3031311700 hasConcept C121608353 @default.
• W3031311700 hasConcept C126322002 @default.
• W3031311700 hasConcept C154945302 @default.
• W3031311700 hasConcept C169573571 @default.
• W3031311700 hasConcept C171250308 @default.
• W3031311700 hasConcept C185592680 @default.
• W3031311700 hasConcept C186060115 @default.
• W3031311700 hasConcept C192562407 @default.
• W3031311700 hasConcept C2777790068 @default.
• W3031311700 hasConcept C2779849746 @default.
• W3031311700 hasConcept C2780192828 @default.
• W3031311700 hasConcept C2994372470 @default.
• W3031311700 hasConcept C40003534 @default.
• W3031311700 hasConcept C41008148 @default.
• W3031311700 hasConcept C54355233 @default.
• W3031311700 hasConcept C71924100 @default.

• next