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- W3031367808 abstract "目的 了解妊娠期外阴阴道念珠菌病(Vulvovaginal Candidiasis,VVC)的发生率,母婴垂直传播及新生儿相关病率.方法2002年至2003年在北京妇产医院产前检查和分娩的252例孕妇行阴道真菌涂片、培养及菌种鉴定,其分娩新生儿行皮肤真菌培养及菌种鉴定,并随诊新生儿.结果252例孕妇阴道真菌涂片和/或培养阳性109例,阳性率43.25%.妊娠期VVC的发病率为19.05%(48/252).109例阳性患者中,剖宫产与阴道分娩儿皮肤真菌携带率分别为20.76%(11/53)和35.71%(20/56),P＞0.05;孕期VVC组与真菌携带组新生儿皮肤真菌携带率分别为16.67%(8/48)和37.71%(23/61),P＜0.05;孕期治疗组新生儿无真菌携带;未治疗组新生儿真菌携带率为50.82%(31/61).252例中新生儿真菌培养(+)31例,真菌携带率为12.30%;真菌培养(+)的新生儿尿布皮炎、鹅口疮的发生率为12.90%(4/31)和6.45%(2/31);与新生儿真菌培养(-)组[3.62%(8/221)和0%]相比,P＜0.05.阴道真菌涂片和/或培养阳性109例中,剖宫产组新生儿脐炎、尿布皮炎、鹅口疮的发病率[分别为3.77%(2/53)、15.09%(8/53)和1.87%(1/53)]与阴道分娩组[分别为1.79%(1/56)、7.14%(4/56)和1.79%(1/56)]相比无统计学意义(P＞0.05).孕期真菌阳性未治疗组新生儿脐炎、尿布皮炎、鹅口疮的发病率[分别为4.92%(3/61)、19.67%(12/61)和3.28%(2/61)]高于治疗组(无新生儿发病).结论孕期存在真菌母婴垂直传播.妊娠合并VVC者新生儿相关疾病发病率高。" @default.
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- W3031367808 date "2005-05-16" @default.
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- W3031367808 title "Vulvovaginal candidiasis and its impact on newborns" @default.
- W3031367808 doi "https://doi.org/10.3760/cma.j.issn.1007-9408.2005.03.008" @default.
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