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- W3031386753 abstract "ObjectiveTo observe the food intolerance of irritable bowel syndrome with diarrhoea(IBS-D) patients and healthy physical examinees and the clinical effect of the treatment of IBS-D food rejectingtrend.MethodsSixty-eight cases IBS-D patients meeting the diagnostic criteria of RomeⅢ were selected and 40 cases of healthy as control group, tested 14 kinds of food specific IgG antibody by enzyme-linked immunosorbent assay, treated the IBS-D patients with food intolerance for 12 weeks by the application of food rejectingtrend and observed the change of main symptoms.ResultsAmong the 68 cases of IBS-D patients, 55 cases had at least one of food intolerance, the positive rate was 80.88%; the control group had 13 cases of food intolerance, the positive rate was 32.50%, the difference between the two groups was statistically significant(χ2=25.28, P<0.01). The food with the highest positive rates of two groups were both wheat, egg white/egg yolk, milk and soybean.After 12 weeks of diet treatment, the total score of the symptoms of IBS-D patients decreased from (8.25±2.97) points to (3.13±3.52) points(t=11.107, P<0.01), self scores of the degree 0and frequency of abdominal pain, frequency of diarrhea, degree of abdominal distension, stool shape and general feelings of distress were significantly improved compared with that before treatment(t=12.429, 11.016, 5.685, 5.558, 7.681, 11.065, P<0.01). Among 54 cases IBS-D patients(1 patient lost to follow-up), 61.11%(33/54) significantly improved, 24.07%(13/54) improved, 14.81%(8/54) invalid, the total effective rate was 85.19%(46/54).ConclusionThere is correlation between food intolerance and IBS-D.According to the Results of the detection of food specific IgG antibody, food rejectingtrend treatment can effectively improve the symptoms of IBS-D.Key words: Irritable bowel syndrome with diarrhoea; Food specific IgG antibody; Food rejectingtrend" @default.
- W3031386753 created "2020-06-05" @default.
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- W3031386753 date "2017-03-01" @default.
- W3031386753 modified "2023-09-28" @default.
- W3031386753 title "Clinical research of treating irritable bowel syndrome with diarrhoea with food rejectingtrend" @default.
- W3031386753 doi "https://doi.org/10.3760/cma.j.issn.1008-6315.2017.03.008" @default.
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