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- W3031445834 abstract "目的分析中晚孕期重度子痫前期孕妇胎盘–胎儿血流动力学特点,寻找子痫前期的有效预测指标。方法选择2014年2月至2015年2月在郑州大学第三附属医院诊断为重度子痫前期的120例孕妇为研究组,子痫前期的诊断标准按照国际妊娠期高血压疾病研究协会的规定;并随机选取同期血压正常的健康孕妇120例为对照组。应用三维能量多普勒超声技术检测2组孕妇中晚孕期胎盘血管指数、血流指数、血管血流指数等血流灌注指标;应用多普勒超声技术检测2组脐动脉、大脑中动脉、静脉导管的血流指数。采用t检验、方差分析或秩和检验进行统计学分析,对各参数进行受试者工作特征曲线分析。结果研究组孕≥25~<30、≥30~<34、≥34~<37和≥37周脐动脉收缩期/舒张期流速比值、搏动指数、阻力指数均高于同孕周对照组(P值均<0.001);大脑中动脉收缩期/舒张期流速比值、搏动指数、阻力指数均低于同孕周对照组(P值均<0.01或0.001);静脉导管的心室收缩期峰值血流速度/最大心房收缩期回流速度、静脉搏动指数、静脉前负荷指数、静脉峰值流速指数均高于同孕周对照组(P值均<0.001或0.05)。研究组静脉搏动指数孕≥25~<30周低于同孕周对照组(P<0.001),但孕≥30~<34、≥34~<37和≥37周均高于同孕周对照组(P值均<0.001);静脉前负荷指数孕≥25~<30周低于同孕周对照组(P<0.001),但孕≥30~<34、≥34~<37和≥37周均高于同孕周对照组(P值均<0.001);静脉峰值流速指数均高于同孕周对照组(P值均<0.05);胎盘血管指数、血流指数、血管血流指数均低于同孕周对照组(P值均<0.05)。预测重度子痫前期诊断价值最高的指标是血流指数,以血流指数<34.6为截断值预测重度子痫前期的敏感度为96.7%,特异度为90.8%。结论中晚孕期重度子痫前期孕妇胎盘血流灌注减少,胎儿血流阻力升高。胎盘血流指数预测重度子痫前期价值最高,三维能量多普勒超声开辟了重度子痫前期研究的新视窗。" @default.
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- W3031445834 date "2016-12-16" @default.
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- W3031445834 title "Placenta-fetal hemodynamics among severe preeclampsia women at second and third trimester" @default.
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