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- W3031454190 abstract "ObjectiveTo analyze the efficacy of bronchoalveolar lavage (BAL) combined with non-invasive ventilation on severe pneumonia complicated with respiratory failure.MethodsA total of 120 patients with severe pneumonia complicated with respiratory failure treated in Jinzhong Hospital of Traditional Chinese Medicine from May 2014 to May 2017 were selected. The 50 cases in the control group were treated by non-invasive ventilation, and the 70 cases in the experimental group were treated by non-invasive ventilation combined with BAL. One week after treatment, the therapeutic effect, blood gas indexes (PaO2, PaCO2, SaO2), lung function indexes (FEV1, FEF, DLCO), inflammation indexes (HMGB-1, sTREM, IFN-gamma) were compared between the two groups.ResultsThe effective rate in the experimental group (95.0%) was higher than that in the control group (80.0%), and the difference was significant (χ2=10.29, P<0.05). After treatment, the blood gas indexes in the experimental group were better than those in the control group, and the differences were significant (P<0.05). After treatment, the pulmonary ventilation function of the experimental group was better than that of the control group (P<0.05). The improvement of lung inflammation in the experimental group was better than that in the control group, and the difference was significant (P<0.05).ConclusionsNon-invasive ventilation combined with BAL can effectively treat pulmonary inflammatory response, improve the lung ventilation function and blood gas index, and improve the therapeutic effect.Key words: Bronchoscopy alveolar lavage; Non-invasive ventilation; Severe pneumonia; Respiratory failure" @default.
- W3031454190 created "2020-06-05" @default.
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- W3031454190 date "2019-01-25" @default.
- W3031454190 modified "2023-09-23" @default.
- W3031454190 title "Effect of bronchoalveolar lavage combined with non-invasive ventilation on severe pneumonia complicated with respiratory failure" @default.
- W3031454190 doi "https://doi.org/10.3760/cma.j.issn.1674-4756.2019.02.022" @default.
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