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- W3031570254 abstract "ObjectiveTo analyze the expression of erythropoietin producing human hepatocellular receptor A2(EphA2)and CD133 in gastric carcinoma and their relationship with clinicopathological features and the prognosis of gastric carcinoma.MethodsEnvision immunohistochemical method was used to assess the expression of EphA2 and CD133 in 82 cases of human gastric carcinoma tissues and non-cancerous adjacent gastric tissues.ResultsThe expression rate of EphA2 in gastric carcinoma tissues was higher than that in non-cancerous adjacent gastric tissues(86.59% vs.20.73%,P< 0.01). The expression rate of CD133 in gastric carcinoma tissues was higher than that in non-cancerous adjacent gastric tissues(67.07% vs.10.98%,P< 0.01).The expression of Eph A2 was related to TNM stage and lymph node metastasis of gastric carcinoma(P< 0.05). There was a close correlation between the expression of CD133 and histological grade, TNM stage and lymph node metastasis(P<0.05).ConclusionThe overexpression of EphA2 and CD133 may play certain roles in the pathogenesis of gastric carcinoma.Key words: Gastric carcinoma; Eerythropoietin producing human hepatocellular receptor A2; CD133; Immunohistochemical method" @default.
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- W3031570254 date "2015-01-08" @default.
- W3031570254 modified "2023-09-23" @default.
- W3031570254 title "Expression of erythropoietin producing human hepatocellular receptor A2 and CD133 in gastric carcinoma and their correlation with development of gastric cancer" @default.
- W3031570254 doi "https://doi.org/10.3760/cma.j.issn.1001-9030.2015.01.060" @default.
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