Matches in SemOpenAlex for { <https://semopenalex.org/work/W3031578082> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W3031578082 abstract "Insulin resistance is impaired insulin signaling cascade in target cells to respond normal or elevated circulating insulin to the final cellular effect, such as translocation of vesicles containing GLUT4 glucose transporters, which is the major mediator of glucose removal from the circulation and a key regulator of whole-body glucose homeostasis. Among the several plants, Andrographis peniculata (sambiloto) and Syzygium polyanthum (Daun salam). Methods In the present study, a combination was made, Andrographis peniculata (sambiloto) and Syzygium polyanthum (Daun salam), and to determine the effects of combination on tretament insulin resistance. Male Wistar rats (weight, 200-300 g) were randomized into five groups (6 rats/group). Group 1: negative group. Group 2: positive group (metformin 63 mg/kgBW ). Group 3,4 and 5: treatment with extract combination, each group 250 mg/kgBW, 500 mg/kgBW and 1000 mg/kgBW. Rats were induced by high fat diet-glucocorticoid for insulin resistance. Insulin and GLUT-4 were assayed by ELISA. Results Treatment with extract combination (250, 500 and 1000 mg/kgBW) and metformin for 2 weeks showed a sigificant decrease in fasting plasma insulin compare with the negative control rats with a reduction of 11,2%, 33,6%, 20% and 19,4%, respectively. Conclusions Two weeks treatment either extract combination or metformin in diabetic rats, significantly increased GLUT 4 level (p<0,05) with a percentage increase of 6,68%, 15,21%, 12,76% and 1,77%." @default.
- W3031578082 created "2020-06-05" @default.
- W3031578082 creator A5028330389 @default.
- W3031578082 date "2018-11-01" @default.
- W3031578082 modified "2023-09-26" @default.
- W3031578082 title "Peer Review_Irsan_Saleh_The Efficacy of Combination Extract Andrographis peniculata and Syzygium polyanthum on Glucose Uptake in Skletal Muscle in Diabetic Rats" @default.
- W3031578082 hasPublicationYear "2018" @default.
- W3031578082 type Work @default.
- W3031578082 sameAs 3031578082 @default.
- W3031578082 citedByCount "0" @default.
- W3031578082 crossrefType "journal-article" @default.
- W3031578082 hasAuthorship W3031578082A5028330389 @default.
- W3031578082 hasConcept C126322002 @default.
- W3031578082 hasConcept C134018914 @default.
- W3031578082 hasConcept C142724271 @default.
- W3031578082 hasConcept C161573976 @default.
- W3031578082 hasConcept C204787440 @default.
- W3031578082 hasConcept C2776188179 @default.
- W3031578082 hasConcept C2777391703 @default.
- W3031578082 hasConcept C2777866211 @default.
- W3031578082 hasConcept C2777970627 @default.
- W3031578082 hasConcept C2779306644 @default.
- W3031578082 hasConcept C2780323712 @default.
- W3031578082 hasConcept C2781325065 @default.
- W3031578082 hasConcept C556039675 @default.
- W3031578082 hasConcept C71924100 @default.
- W3031578082 hasConcept C98274493 @default.
- W3031578082 hasConceptScore W3031578082C126322002 @default.
- W3031578082 hasConceptScore W3031578082C134018914 @default.
- W3031578082 hasConceptScore W3031578082C142724271 @default.
- W3031578082 hasConceptScore W3031578082C161573976 @default.
- W3031578082 hasConceptScore W3031578082C204787440 @default.
- W3031578082 hasConceptScore W3031578082C2776188179 @default.
- W3031578082 hasConceptScore W3031578082C2777391703 @default.
- W3031578082 hasConceptScore W3031578082C2777866211 @default.
- W3031578082 hasConceptScore W3031578082C2777970627 @default.
- W3031578082 hasConceptScore W3031578082C2779306644 @default.
- W3031578082 hasConceptScore W3031578082C2780323712 @default.
- W3031578082 hasConceptScore W3031578082C2781325065 @default.
- W3031578082 hasConceptScore W3031578082C556039675 @default.
- W3031578082 hasConceptScore W3031578082C71924100 @default.
- W3031578082 hasConceptScore W3031578082C98274493 @default.
- W3031578082 hasLocation W30315780821 @default.
- W3031578082 hasOpenAccess W3031578082 @default.
- W3031578082 hasPrimaryLocation W30315780821 @default.
- W3031578082 hasRelatedWork W1564742724 @default.
- W3031578082 hasRelatedWork W1832121734 @default.
- W3031578082 hasRelatedWork W2016784806 @default.
- W3031578082 hasRelatedWork W2103542046 @default.
- W3031578082 hasRelatedWork W2119506007 @default.
- W3031578082 hasRelatedWork W2142863064 @default.
- W3031578082 hasRelatedWork W2181521494 @default.
- W3031578082 hasRelatedWork W2294786496 @default.
- W3031578082 hasRelatedWork W2760570251 @default.
- W3031578082 hasRelatedWork W2904674943 @default.
- W3031578082 hasRelatedWork W2926066976 @default.
- W3031578082 hasRelatedWork W2993255481 @default.
- W3031578082 hasRelatedWork W3095835684 @default.
- W3031578082 hasRelatedWork W3102164997 @default.
- W3031578082 hasRelatedWork W3103089560 @default.
- W3031578082 hasRelatedWork W3113897813 @default.
- W3031578082 hasRelatedWork W3121405694 @default.
- W3031578082 hasRelatedWork W3124023565 @default.
- W3031578082 hasRelatedWork W3170039534 @default.
- W3031578082 hasRelatedWork W2184839957 @default.
- W3031578082 isParatext "false" @default.
- W3031578082 isRetracted "false" @default.
- W3031578082 magId "3031578082" @default.
- W3031578082 workType "article" @default.