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- W3031585466 abstract "ObjectiveTo evaluate the diagnostic value of prostate imaging reporting and data system version 1 (PI-RADS V1) and version 2 (PI-RADS V2) for detection of prostate cancer (PCa) in the transition zone (TZ).MethodsSeventy-seven patients with suspicious lesions in TZ on mpMRI were scored according to the PI-RADS system (V1 and V2) before MR-TRUS fusion guided biopsy prospectively. In all of the patients with suspicious tumors, respectively at least one lesion with a PI-RADS V1 assessment category of ≥3, was selected for biopsy.Independent sample t test was used to compare scores of PI-RADS V1 and V2 between PCa and benign prostatic hyperplasia (BPH). The diagnostic performance of PI-RADS V1 and V2 for detection of PCa in the transition zone was compared by analyzing ROC basing on the results of MR-TRUS fusion guided biopsy.ResultsA cohort of 77 patients was performed including 31 cases of PCa (32 cores) and 46 cases of BPH (51 cores). PCa (V1:11.50±2.79; V2:4.28±0.99) had significantly higher scores of both PI-RADS V1 and PI-RADS V2 than BPH(V1:7.51±1.63; V2:2.61±0.67) (P<0.05). Using a PI-RADS V1 score cut-off ≥ 11, sensitivity and specificity in group PCa and BPH were calculated, which were 68.8%(22/32) and 96.1%(49/51) with a area under curve of 0.869; using a PI-RADS V2 score cut-off ≥ 4, which were 75.0% (24/32) and 90.2% (46/51) with a area under curve of 0.888, respectively.ConclusionsPI-RADS system can indicate the likelihood of PCa of suspicious lesions in TZ on Mp-MRI. PI-RADS V2 perform better than V1 for the assessment of prostate cancer in TZ.Key words: Prostatic neoplasms; Magnetic resonance imaging; Prostate imaging reporting and data system; Comparative study" @default.
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- W3031585466 date "2017-06-10" @default.
- W3031585466 modified "2023-09-28" @default.
- W3031585466 title "Diagnostic value of prostate imaging reporting and data system version 1 and 2 in detection of prostate cancer in transition zone" @default.
- W3031585466 doi "https://doi.org/10.3760/cma.j.issn.1005-1201.2017.06.006" @default.
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