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- W3031625101 abstract "目的 探讨电针治疗老年性痴呆的突触可塑性机制,为老年性痴呆的针灸作用机理研究提供新的思路.方法SD大鼠随机分为对照组、模型组、假手术组和电针组;以穹隆-海马伞切断进行老年性痴呆造模,电针百会、涌泉、太溪、血海后,电镜观察海马CA3区突触形态可塑性指标突触数密度(Nv)、突触面密度(Sv)及平均面积(S)的变化.结果模型组大鼠的Nv(2.16±0.17)、Sv(0.09±0.02)较对照组(6.16±0.96,0.27±0.05)明显减少(P＜0.01);电针组大鼠的Nv(5.08±1.02)、Sv(0.23±0.04)较模型组明显增加(P＜0.01).模型组(0.20±0.03)大鼠S较对照组(0.04±0.01)明显增加(P＜0.01);电针组大鼠的S(0.06±0.01)较模型组明显减少(P＜0.01).结论电针百会、涌泉、太溪、血海具有一定程度的促进突触可塑性发挥的作用。" @default.
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- W3031625101 date "2006-04-15" @default.
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- W3031625101 title "Effect of electroacupuncture therapy on morphological synaptic plasticity in hippocampal neurons of rats with senile dementia" @default.
- W3031625101 doi "https://doi.org/10.3760/cma.j.issn.1671-8925.2006.04.011" @default.
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