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- W3031689595 abstract "ObjectiveTo analyze the difference among the 3 guidelines used to make surgical decision for branch duct intraductal papillary mucinous neoplasm (BD-IPMN), then the guidelines were combined with neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) respectively for further analysis.MethodsClinical data of 51 appropriate BD-IPMN patients who underwent surgical resection from January 2008 to December 2015 was retrospectively analyzed.ResultsThe significant difference was exist in the consensus for followup criterion (P<0.05). The preoperative NLR and PLR were helpful for the differential diagnosis between malignant and benign BD-IPMN, because the receiver operating characteristic curve (ROC) of NLR and PLR for prediction were 0.686 and 0.692, and the best boundary values were 2.64, 92.56 respectively. The consensus combined with PLR could improve the specificity and positive predictive value (PPV), besides, the specificity and PPV could achieve 70.3%, 54.2% respectively while the sensitivity (92.9%) still remained at an ideal level after international consensus guideline combined with PLR.ConclusionsNLR≥2.64 and PLR≥92.56 were predictive markers for the presence of BD-IPMN associated invasive tumor. The addition of PLR as a criterion to the international consensus guideline improved the accuracy of international consensus guidelines in estimating invasive BD-IPMN.Key words: Pancreatic neoplasms; Diagnosis; NLR; PLR" @default.
- W3031689595 created "2020-06-05" @default.
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- W3031689595 date "2017-09-25" @default.
- W3031689595 modified "2023-09-23" @default.
- W3031689595 title "The value of preoperative NLR and PLR combined with the consensus in surgical decision making for branch duct intraductal papillary mucinous neoplasm of the pancreas" @default.
- W3031689595 doi "https://doi.org/10.3760/cma.j.issn.1007-631x.2017.09.004" @default.
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