Matches in SemOpenAlex for { <https://semopenalex.org/work/W3031691034> ?p ?o ?g. }
Showing items 1 to 58 of
58
with 100 items per page.
- W3031691034 endingPage "52" @default.
- W3031691034 startingPage "48" @default.
- W3031691034 abstract "Filtration surgery is still the major operative intervention to glaucoma. The failure (recurrence) rate of the surgery remains high due to the scarring of the filtration zone as the result of fibroblast hyperplasia. To improve the success rate of the surgery, a variety of anti-fibrotic agents have been used in the clinic, which may be potentially accompanied by unwanted adverse reaction/side effect and complications. With better understanding of the scarring process, progress on the development of anti-scarring agents with high efficiency but less side effects has achieved to improve the outcome of filtration surgery. Novel anti-fibrotic agents are under investigation recently, including anti-vascular endothelial growth factor, pirfenidone, suramin, sphingosine-1-phosphate antibody, suberoylanilide hydroxamic acid, tissue inhibitor of metalloproteinase, microRNA, gene therapy and nano-drugs. The researches regarding the effectiveness and safety of these novel agents are still preliminary. Further studies on the pharmacokinetics of these drugs needs to be carried out, including the dosage, timing and frequency of drug administration.(Int Rev Ophthalmol, 2018, 42: 48-52)Key words: glaucoma; filtration surgery; anti-fibrotic therapy" @default.
- W3031691034 created "2020-06-05" @default.
- W3031691034 creator A5051014731 @default.
- W3031691034 creator A5075162983 @default.
- W3031691034 date "2018-02-22" @default.
- W3031691034 modified "2023-09-26" @default.
- W3031691034 title "Progress on anti-fibrotic therapy after glaucoma filtration surgery" @default.
- W3031691034 doi "https://doi.org/10.3760/cma.j.issn.1673-5803.2018.01.012" @default.
- W3031691034 hasPublicationYear "2018" @default.
- W3031691034 type Work @default.
- W3031691034 sameAs 3031691034 @default.
- W3031691034 citedByCount "0" @default.
- W3031691034 crossrefType "journal-article" @default.
- W3031691034 hasAuthorship W3031691034A5051014731 @default.
- W3031691034 hasAuthorship W3031691034A5075162983 @default.
- W3031691034 hasConcept C118487528 @default.
- W3031691034 hasConcept C141071460 @default.
- W3031691034 hasConcept C2776766258 @default.
- W3031691034 hasConcept C2778527774 @default.
- W3031691034 hasConcept C2781092963 @default.
- W3031691034 hasConcept C71924100 @default.
- W3031691034 hasConceptScore W3031691034C118487528 @default.
- W3031691034 hasConceptScore W3031691034C141071460 @default.
- W3031691034 hasConceptScore W3031691034C2776766258 @default.
- W3031691034 hasConceptScore W3031691034C2778527774 @default.
- W3031691034 hasConceptScore W3031691034C2781092963 @default.
- W3031691034 hasConceptScore W3031691034C71924100 @default.
- W3031691034 hasIssue "1" @default.
- W3031691034 hasLocation W30316910341 @default.
- W3031691034 hasOpenAccess W3031691034 @default.
- W3031691034 hasPrimaryLocation W30316910341 @default.
- W3031691034 hasRelatedWork W2027731601 @default.
- W3031691034 hasRelatedWork W2057262806 @default.
- W3031691034 hasRelatedWork W2066953275 @default.
- W3031691034 hasRelatedWork W2198394533 @default.
- W3031691034 hasRelatedWork W2298265134 @default.
- W3031691034 hasRelatedWork W2400599372 @default.
- W3031691034 hasRelatedWork W2416810411 @default.
- W3031691034 hasRelatedWork W3008160452 @default.
- W3031691034 hasRelatedWork W3029688118 @default.
- W3031691034 hasRelatedWork W3030653579 @default.
- W3031691034 hasRelatedWork W3030728524 @default.
- W3031691034 hasRelatedWork W3030763447 @default.
- W3031691034 hasRelatedWork W304295703 @default.
- W3031691034 hasRelatedWork W3043429439 @default.
- W3031691034 hasRelatedWork W3046351430 @default.
- W3031691034 hasRelatedWork W3136974098 @default.
- W3031691034 hasRelatedWork W3205110195 @default.
- W3031691034 hasRelatedWork W6310631 @default.
- W3031691034 hasRelatedWork W86174747 @default.
- W3031691034 hasRelatedWork W2952028663 @default.
- W3031691034 hasVolume "42" @default.
- W3031691034 isParatext "false" @default.
- W3031691034 isRetracted "false" @default.
- W3031691034 magId "3031691034" @default.
- W3031691034 workType "article" @default.