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- W3031700691 abstract "ObjectiveTo explore the clinical features and etiological factors of necrotizing enterocolitis (NEC) after enteral nutrition (EN) for neonates with congenital intestinal atresia.MethodsThe clinical data were analyzed retrospectively for 6 pediatric cases of NEC from December 2012 to January 2017. There were 3 boys and 3 girls. And the neonates were premature (n=3) and low-birth-weight (n=3). The primary types of intestinal atresia were duodenal (n=1), jejunal (n=4) and ileal (n=1). Concomitant congenital gastrointestinal diseases included intestinal malrotation (n=1) and meconium peritonitis (n=1). Postoperative trans-nasojejunal tube feeding EN (n=4) and oral feeding (n=2) were performed. The average age of NEC onset was 16.67(11-24) days and the average duration of EN 6(2-11) days prior to NEC.ResultsThree cases were cured by conservative measures and 2 underwent laparotomy. One case of focal small intestinal necrosis underwent intestinal anastomosis and recovered postoperatively. One case of whole intestinal necrosis gave up while another case was discharged automatically after a definite diagnosis of NEC.ConclusionsThe specific pathogenesis of NEC after intestinal atresia remains elusive. Preterm birth, low birth weight and concomitant congenital gastrointestinal diseases are high risk factors. Early enteral nutrition may be one of the causes of NEC. Tolerability assessment of EN should be performed timely. And aggressive surgery should be performed for ineffective cases after 24-48 hours of conservative measures.Key words: Intestinal atresia; Necrotizing enterocolitis; Enteral nutrition" @default.
- W3031700691 created "2020-06-05" @default.
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- W3031700691 date "2019-04-15" @default.
- W3031700691 modified "2023-09-24" @default.
- W3031700691 title "Necrotizing enterocolitis after enteral nutrition for neonates with congenital intestinal atresia" @default.
- W3031700691 doi "https://doi.org/10.3760/cma.j.issn.0253-3006.2019.04.008" @default.
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