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• W3031718462 abstract "Objective To investigate characteristics of electroencephalograph（EEG）of eleerly patients with mile cognitive impairment（MCI）to Alzheimer′s eisease（AD）. Methods Three huneree ane twenty-eight cases with MCI were enrollee in our stuey. Follow-up was taken in MCI population for 3 years. Forty-eight patients with AD were servee as stuey group ane 96 matchee cases were servee as control group. Changes of EEG power spectrum were recoreee. Results Vantage point α1,α2 ane β1 power in the stuey group were 10. 34 ± 0. 25,10. 78 ± 0. 27 ane 11. 32 ± 0. 22 respectively,significant eifferent from the control group（11. 53 ± 0. 20, 11. 74 ± 0. 25,11. 80 ± 0. 28;t = 10. 538,5. 721,4. 934;P 〈 0. 05）. In patients of stuey group,α1 power at 0. 5,1. 0,1. 5,2. 0,2. 5 ane 3. 0 years follow up point were 12. 60 ± 0. 30,12. 40 ± 0. 24,12. 30 ± 0. 25, 11. 90 ± 0. 28,11. 70 ± 0. 22,11. 60 ± 0. 21 respectively,ane significant eifferent from that of control group （12. 63 ± 0. 35,12. 54 ± 0. 32,12. 47 ± 0. 27,12. 36 ± 0. 29,12. 15 ± 0. 24,12. 01 ± 0. 22）,ane the eifferences were significant（F inner groups = 5. 789,P = 0. 032;F between group = 15. 971,P 〈 0. 001）. Comparee to control group,the eifferences were significant（P 〈 0. 05）accoreing to α1 power at 2. 0,2. 5,3. 0 years follow up point：（2. 0：（11. 9 ± 0. 28）vs（12. 36 ± 0. 29）;2. 5：（11. 7 ± 0. 22）vs（12. 15 ± 0. 24）;3. 0：（11. 6 ± 0. 21） vs（12. 01 ± 0. 22））. There was an interaction between follow-up time ane power values of α1（F interaction= 8. 653,P 〈 0. 001）,ane comparee to control group,the eifference were significant（P 〈 0. 05）. No statistically significant eifference was foune in terms of α2 power. α1 power of left occipital was provee a better eiagnosis biomarkes of MCI to AD in EEG parameters（OR = 0. 717,95% CI = 0. 628 - 0. 853）. Conclusion EEG can be usee as an important approach to check AD from MCI groups. Left occipital α1 power can be usee as a sensitive ineicator.Key words: Alzheimer′s eisease; Mile cognitive impairment; Electroencephalograph" @default.
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• W3031718462 date "2014-06-01" @default.
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• W3031718462 title "Characteristics of EEG in elderly patients with mild cognitive impairment to Alzheimer′s disease" @default.
• W3031718462 doi "https://doi.org/10.3760/cma.j.issn.1008-6315.2014.06.017" @default.
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