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- W3031722831 abstract "目的 研究角膜上皮培养移植后角膜新生血管(CNV)形成和血管内皮生长因子(VEGF)的变化特点.方法 对角膜碱烧伤CNV大鼠行培养角膜上皮移植,观察术后CNV程度,RT-PCR和免疫组织化学法检测术后24、48、72、168 h角膜组织VEGF的表达.结果 实验组角膜上皮移植后14 d CNV接近瞳孔区,之后逐渐减退.移植后24 h角膜VEGF mRNA的相对含量为1 20±0.09;48 h为1 91±0.03;72 h为2.34±0.11;168 h为1.83 ±0.14.角膜上皮和基质均表达VEGF蛋白,以上皮层表达为主,并随时间推移表达量增加.结论 培养角膜上皮移植后24 h角膜可表达VEGF,72 h表达量最高.VEGF表达与培养角膜上皮移植后CNV的发生密切相关。" @default.
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- W3031722831 date "2008-01-15" @default.
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- W3031722831 title "Expression of vascular endothelial growth factor in rat cornea after corneal epithelium transplantation for alkali burn" @default.
- W3031722831 doi "https://doi.org/10.3760/cma.j.issn.2095-0160.2008.01.003" @default.
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