Matches in SemOpenAlex for { <https://semopenalex.org/work/W3031726837> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W3031726837 endingPage "109882" @default.
- W3031726837 startingPage "109882" @default.
- W3031726837 abstract "The current SARS-CoV-2 has put significant strain on healthcare services worldwide due to acute COVID-19. However, the potential long-term effects of this infection haven’t been extensively discussed. We hypothesize that SARS-CoV-2 may be able to cause persistent infection in some individuals, and should this be the case, that in a few years we may see a rise in cancer incidence due to carcinogenic effects of this coronavirus. Non-retroviral RNA viruses such as Coronaviridae have been shown to cause persistent infection in hosts. Empirical evidence of viral genomic material shedding weeks after apparent clinical and laboratorial resolution of COVID-19 may be an indirect proof for persistent viral infection. Furthermore, tropism towards certain immune-privileged territories may facilitate immune evasion by this virus. Structural homology with SARS-CoV-1 indicates that SARS-CoV-2 may be able to directly impair pRb and p53, which are key gatekeepers with tumor suppressor functions. Additionally, COVID-19 features preeminent inflammatory response with marked oxidative stress, which acts as both as initiator and promotor of carcinogenesis. Should there be a carcinogenic risk associated with SARS-CoV-2, the implications for public health are plenty, as infected patients should be closely watched during long periods of follow-up. Additional investigation to establish or exclude the possibility for persistent infection is paramount to identify and prevent possible complications in the future." @default.
- W3031726837 created "2020-06-05" @default.
- W3031726837 creator A5006150656 @default.
- W3031726837 creator A5021642297 @default.
- W3031726837 creator A5043446197 @default.
- W3031726837 date "2020-10-01" @default.
- W3031726837 modified "2023-10-17" @default.
- W3031726837 title "Persistent SARS-CoV-2 infection and the risk for cancer" @default.
- W3031726837 cites W2026618142 @default.
- W3031726837 cites W2040380370 @default.
- W3031726837 cites W2094156327 @default.
- W3031726837 cites W2102032371 @default.
- W3031726837 cites W2153243197 @default.
- W3031726837 cites W2516727366 @default.
- W3031726837 cites W2595587791 @default.
- W3031726837 cites W3009494406 @default.
- W3031726837 cites W3013442544 @default.
- W3031726837 cites W3014310029 @default.
- W3031726837 cites W3017125154 @default.
- W3031726837 cites W3017291089 @default.
- W3031726837 cites W3017324456 @default.
- W3031726837 doi "https://doi.org/10.1016/j.mehy.2020.109882" @default.
- W3031726837 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7831646" @default.
- W3031726837 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32485314" @default.
- W3031726837 hasPublicationYear "2020" @default.
- W3031726837 type Work @default.
- W3031726837 sameAs 3031726837 @default.
- W3031726837 citedByCount "24" @default.
- W3031726837 countsByYear W30317268372020 @default.
- W3031726837 countsByYear W30317268372021 @default.
- W3031726837 countsByYear W30317268372022 @default.
- W3031726837 countsByYear W30317268372023 @default.
- W3031726837 crossrefType "journal-article" @default.
- W3031726837 hasAuthorship W3031726837A5006150656 @default.
- W3031726837 hasAuthorship W3031726837A5021642297 @default.
- W3031726837 hasAuthorship W3031726837A5043446197 @default.
- W3031726837 hasBestOaLocation W30317268371 @default.
- W3031726837 hasConcept C121608353 @default.
- W3031726837 hasConcept C12914427 @default.
- W3031726837 hasConcept C142724271 @default.
- W3031726837 hasConcept C159047783 @default.
- W3031726837 hasConcept C203014093 @default.
- W3031726837 hasConcept C2522874641 @default.
- W3031726837 hasConcept C2776844884 @default.
- W3031726837 hasConcept C2777648638 @default.
- W3031726837 hasConcept C2779134260 @default.
- W3031726837 hasConcept C3007834351 @default.
- W3031726837 hasConcept C3008058167 @default.
- W3031726837 hasConcept C35693153 @default.
- W3031726837 hasConcept C524204448 @default.
- W3031726837 hasConcept C54355233 @default.
- W3031726837 hasConcept C555283112 @default.
- W3031726837 hasConcept C71924100 @default.
- W3031726837 hasConcept C86803240 @default.
- W3031726837 hasConcept C8891405 @default.
- W3031726837 hasConceptScore W3031726837C121608353 @default.
- W3031726837 hasConceptScore W3031726837C12914427 @default.
- W3031726837 hasConceptScore W3031726837C142724271 @default.
- W3031726837 hasConceptScore W3031726837C159047783 @default.
- W3031726837 hasConceptScore W3031726837C203014093 @default.
- W3031726837 hasConceptScore W3031726837C2522874641 @default.
- W3031726837 hasConceptScore W3031726837C2776844884 @default.
- W3031726837 hasConceptScore W3031726837C2777648638 @default.
- W3031726837 hasConceptScore W3031726837C2779134260 @default.
- W3031726837 hasConceptScore W3031726837C3007834351 @default.
- W3031726837 hasConceptScore W3031726837C3008058167 @default.
- W3031726837 hasConceptScore W3031726837C35693153 @default.
- W3031726837 hasConceptScore W3031726837C524204448 @default.
- W3031726837 hasConceptScore W3031726837C54355233 @default.
- W3031726837 hasConceptScore W3031726837C555283112 @default.
- W3031726837 hasConceptScore W3031726837C71924100 @default.
- W3031726837 hasConceptScore W3031726837C86803240 @default.
- W3031726837 hasConceptScore W3031726837C8891405 @default.
- W3031726837 hasLocation W30317268371 @default.
- W3031726837 hasLocation W30317268372 @default.
- W3031726837 hasOpenAccess W3031726837 @default.
- W3031726837 hasPrimaryLocation W30317268371 @default.
- W3031726837 hasRelatedWork W2002481497 @default.
- W3031726837 hasRelatedWork W2044069055 @default.
- W3031726837 hasRelatedWork W3046362782 @default.
- W3031726837 hasRelatedWork W3048705100 @default.
- W3031726837 hasRelatedWork W3109411001 @default.
- W3031726837 hasRelatedWork W3160595510 @default.
- W3031726837 hasRelatedWork W3205206809 @default.
- W3031726837 hasRelatedWork W3217468344 @default.
- W3031726837 hasRelatedWork W4206170635 @default.
- W3031726837 hasRelatedWork W3016461735 @default.
- W3031726837 hasVolume "143" @default.
- W3031726837 isParatext "false" @default.
- W3031726837 isRetracted "false" @default.
- W3031726837 magId "3031726837" @default.
- W3031726837 workType "article" @default.