Matches in SemOpenAlex for { <https://semopenalex.org/work/W3031777691> ?p ?o ?g. }
- W3031777691 endingPage "72" @default.
- W3031777691 startingPage "61" @default.
- W3031777691 abstract "This review summarizes current in vitro tools used for developing engineered heart muscle and studying the response of these tissues to mechanical loading changes that simulate the mechanical cues that heart muscle experiences in vivo. Advances in stem cell technology allow researchers to model genetically inherited disease phenotypes in vitro. However, one major challenge for in vitro disease modeling and drug screening is that the cardiomyocytes in simple monolayer culture are normally not exposed to the mechanical stimuli that the heart experiences in vivo. Mechanical loading is critical to heart development and pathophysiology. In vitro models have shown that cells in culture can respond to mechanical conditioning, and in some cases, this condition is critical for maturing stem cell-derived cardiomyocytes. Tools from mechanobiology have broadened the view of how physical cues guide cardiomyocyte behavior and function. This review highlights in vitro technologies for developing cardiac models and studying cardiac responses to mechanical loading." @default.
- W3031777691 created "2020-06-05" @default.
- W3031777691 creator A5002024736 @default.
- W3031777691 creator A5065756622 @default.
- W3031777691 date "2020-05-30" @default.
- W3031777691 modified "2023-10-15" @default.
- W3031777691 title "Modeling the Response of Heart Muscle to Mechanical Stimulation In Vitro" @default.
- W3031777691 cites W1522672235 @default.
- W3031777691 cites W1560201504 @default.
- W3031777691 cites W165232971 @default.
- W3031777691 cites W1802031919 @default.
- W3031777691 cites W1966140207 @default.
- W3031777691 cites W1966501485 @default.
- W3031777691 cites W1976805840 @default.
- W3031777691 cites W1998860713 @default.
- W3031777691 cites W2000206662 @default.
- W3031777691 cites W2002708055 @default.
- W3031777691 cites W2006743934 @default.
- W3031777691 cites W2007279845 @default.
- W3031777691 cites W2016157842 @default.
- W3031777691 cites W2016279653 @default.
- W3031777691 cites W2017080249 @default.
- W3031777691 cites W2022229270 @default.
- W3031777691 cites W2022859917 @default.
- W3031777691 cites W2024763420 @default.
- W3031777691 cites W2030600914 @default.
- W3031777691 cites W2033765226 @default.
- W3031777691 cites W2035312069 @default.
- W3031777691 cites W2036272929 @default.
- W3031777691 cites W2039371919 @default.
- W3031777691 cites W2039564450 @default.
- W3031777691 cites W2046110995 @default.
- W3031777691 cites W2048015545 @default.
- W3031777691 cites W2053604203 @default.
- W3031777691 cites W2060613028 @default.
- W3031777691 cites W2061698013 @default.
- W3031777691 cites W2062298134 @default.
- W3031777691 cites W2065661375 @default.
- W3031777691 cites W2066390373 @default.
- W3031777691 cites W2067539877 @default.
- W3031777691 cites W2069405557 @default.
- W3031777691 cites W2071145526 @default.
- W3031777691 cites W2074196229 @default.
- W3031777691 cites W2079176005 @default.
- W3031777691 cites W2086321200 @default.
- W3031777691 cites W2086557128 @default.
- W3031777691 cites W2087179870 @default.
- W3031777691 cites W2098188264 @default.
- W3031777691 cites W2101986300 @default.
- W3031777691 cites W2104475665 @default.
- W3031777691 cites W2104790299 @default.
- W3031777691 cites W2106607929 @default.
- W3031777691 cites W2107766408 @default.
- W3031777691 cites W2108903695 @default.
- W3031777691 cites W2113927644 @default.
- W3031777691 cites W2115177875 @default.
- W3031777691 cites W2115230397 @default.
- W3031777691 cites W2115644752 @default.
- W3031777691 cites W2116815871 @default.
- W3031777691 cites W2119297562 @default.
- W3031777691 cites W2122349854 @default.
- W3031777691 cites W2125987139 @default.
- W3031777691 cites W2126284874 @default.
- W3031777691 cites W2126956733 @default.
- W3031777691 cites W2133851654 @default.
- W3031777691 cites W2138977668 @default.
- W3031777691 cites W2141241503 @default.
- W3031777691 cites W2142490721 @default.
- W3031777691 cites W2144950329 @default.
- W3031777691 cites W2147296371 @default.
- W3031777691 cites W2158400337 @default.
- W3031777691 cites W2161311376 @default.
- W3031777691 cites W2163068618 @default.
- W3031777691 cites W2165673443 @default.
- W3031777691 cites W2166305181 @default.
- W3031777691 cites W2169859308 @default.
- W3031777691 cites W2171313781 @default.
- W3031777691 cites W2171332611 @default.
- W3031777691 cites W2175892199 @default.
- W3031777691 cites W2176043226 @default.
- W3031777691 cites W2197670103 @default.
- W3031777691 cites W2200325631 @default.
- W3031777691 cites W2215717357 @default.
- W3031777691 cites W2292016096 @default.
- W3031777691 cites W2334483288 @default.
- W3031777691 cites W2338837420 @default.
- W3031777691 cites W2403944530 @default.
- W3031777691 cites W2410732495 @default.
- W3031777691 cites W2521650734 @default.
- W3031777691 cites W2536032352 @default.
- W3031777691 cites W2549976854 @default.
- W3031777691 cites W2579970354 @default.
- W3031777691 cites W2612053462 @default.
- W3031777691 cites W2621877040 @default.
- W3031777691 cites W2754548624 @default.
- W3031777691 cites W2765584642 @default.
- W3031777691 cites W2782837010 @default.
- W3031777691 cites W2794556464 @default.