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- W3031796783 abstract "Interleukin-37 (IL-37) is a new member of the IL-1 family formerly referred to as IL-1F7.Different from other IL-1 family cytokine, IL-37 can down-regulate both systemic and local inflammation, and modulate the host immune response. The immunosuppressive property of IL-37 has been demonstrated in many diseases, including the auto-immune disease, the cancer, and infectious diseases. Nevertheless, the precise mechanism underlying anti-inflammatory response of IL-37 remains to be further elucidated.In this article, we briefly review the discovery of IL-37 especially its potential mechanism with regard to immune suppression secondary to various immune cells.Key words: Interleukin-37; Inflammatory response; Immune function; Immune cell" @default.
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- W3031796783 date "2017-11-08" @default.
- W3031796783 modified "2023-09-27" @default.
- W3031796783 title "The review of developments in the immunoregulation property and potential mechanism of interleukin-37" @default.
- W3031796783 doi "https://doi.org/10.3760/cma.j.issn.1001-9030.2017.11.059" @default.
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