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- W3031884274 abstract "ObjectiveTo explore the character of N450 induced by Stroop Color-Word Task in childhood schizophrenia patients, and the implication for their poor executive function in deficit of conflict detection.MethodsThe event-related potentials from 20 childhood schizophrenia patients and 20 healthy controls were recorded under a Stroop Color-Word Task. The behavior performance, amplitude of N450 induced by Stroop task, and its relationship between were analyzed.Results(1) Behavioral data: Both groups responded to inconsistent stimuli longer than consistent stimuli (F(1,38)=84.24, P 0.05). (2) ERPs results: Patients presented a reduced N450 lower than the healthy controls (F(1, 38)=7.81, P=0.008). There was also a significant interaction between the groups and among the hemispheres (left, midline, right) (F(2, 76)=3.43, P=0.038). (3) Correlation of behavior performance and ERPs: in patients, the behavioral Stroop effect(RTs incongruent-congruent) was positively correlated with the amplitude difference to incongruent-congruent at the Fz, FCz (r>0, P<0.05). The overall Stroop errors in patients correlated negatively with the amplitude difference to incongruent-congruent at Fz, FCz, FC4 (r<0, P<0.05).ConclusionThe amplitude of N450 is lower in childhood schizophrenia patients, and it might be contributed by their abnormal conflict detection.Key words: Schizophrenia; Child; Evoked Potentials; Stroop effect" @default.
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- W3031884274 date "2019-04-05" @default.
- W3031884274 modified "2023-09-28" @default.
- W3031884274 title "Event-related potentials induced by Stroop Color-Word Task in childhood schizophrenia patients" @default.
- W3031884274 doi "https://doi.org/10.3760/cma.j.issn.1006-7884.2019.02.005" @default.
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