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- W3032003465 abstract "ObjectiveTo investigate the safety and efficacy of curettage and excision for giant cell tumor of the cervical spine.MethodsRetrospectively analyzed 6 cases of giant cell tumors patients who underwent surgical resection of cervical spine between April 2006 and July 2015. There were 2 males and 4 females with an average age of 31.3 years old (ranged from 18 to 42 years). Among them, 4 cases were located in C2 vertebral body, 1 case located in C3 vertebral body, 1 case in C4 spinous process and vertebral lamina. In this study, all the 6 patients underwent intralesional surgery, 3 patients were Enneking grade IIA, which 1 case underwent curettage, 2 cases underwent extended curettage; three cases were Enneking grade IIIB, which 1 case underwent extended curettage, and 2 cases underwent subtotal spondylectomy. Three patients received local inactivation of the lesion. One patient received local radiotherapy after first posterior occipital-cervical fixation, and underwent posterior and anterior tumor resection, bone grafting and internal fixation 3 months later. One patient was treated with denosumab preoperatively, 3 patients were treated with bisphosphonates postoperatively. The neurological status was evaluated by Frankel classification pre- and postoperatively, the pain scale was evaluated by Visual Analogue Scale (VAS) pre- and postoperatively. Imaging examination was used to assess the location and the extent of the tumor preoperatively, as well as the tumor recurrence postoperatively.ResultsThe mean follow-up period was 61.1 months (ranged from 25 to 134 months). One case underwent posterior surgery, while other 5 cases underwent anterior and posterior surgery; 3 patients underwent one-stage surgery, 3 patients underwent multi-staged surgery. The mean intraoperative bleeding was 2 142 ml (ranged from 300 to 9100 ml). The mean preoperative VAS score was 3 (ranged from 2 to 5), the neck pain of the patients were all relieved postoperatively, and the mean VAS score was 0. The Frankel grade were E in all 6 patients of pre- and postoperation. One intracranial epidural hematoma occurred on the second day after operation, emergency evacuation of hematoma was then performed and the postoperative recovery was good. At the latest follow-up, no internal fixation loosening or failure occurred, and no tumor recurrence was observed in all patients.ConclusionIntralesional curettage and excision of the cervical spinal giant cell tumor is a safe and effective surgical method which can achieve satisfactory local control and prognosis.Key words: Cervical vertebra; Giant cell tumor of bone; Surgical procedures" @default.
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- W3032003465 date "2018-03-16" @default.
- W3032003465 modified "2023-09-25" @default.
- W3032003465 title "Efficacy of cervical giant cell tumor surgical treatment via lesion" @default.
- W3032003465 doi "https://doi.org/10.3760/cma.j.issn.0253-2352.2018.06.005" @default.
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