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- W3032036721 abstract "目的 观察布地奈德(普米克令舒)吸入疗法对防治儿童肺炎支原体(mycoplasma pneumoniae,MP)感染的疗效.方法 将120例MP感染患儿,在用阿奇霉素或红霉素治疗2～3周的基础上,按照辅助疗法的不同分成4组:原方案组、普米克令舒组、氯雷他定(克敏能)组和胸腺肽或转移因子注射组.用药前后检测外周静脉血嗜酸粒细胞阳离子蛋白(eosinophilic cationic protein,ECP)、嗜酸粒细胞(eosinophilic,EOS)、白介素4(interleukin-4,IL-4)和总IgE(total Immunoglobulin E,T-IgE).结果 普米克令舒吸入组与其它两组疗法的临床症状消失时间,比原方案组显著缩短,而且3个月内反复呼吸道感染次数显著减少.其中,普米克令舒吸入组疗程最短.原方案组除ECP在用药后降低外,IL-4和T-IgE均无明显变化;而原方案加普米克令舒吸入等辅助疗法三组用药后ECP、EOS、IL-4都有明显下降,差异有统计学意义,T-IgE水平基本无变化.结论 在缩短疗程方面,加用小剂量激素吸入疗法是首选的辅助疗法;免疫调节剂和抗过敏药物能够促进儿童MP感染后的康复,降低复发频率,从而提高儿童MP感染的防治水平。" @default.
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- W3032036721 date "2007-04-20" @default.
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- W3032036721 title "Budesonide inhaling auxiliary therapy after mycoplasma pneumoniae infection of children" @default.
- W3032036721 doi "https://doi.org/10.3760/cma.j.issn.1673-436x.2007.08.003" @default.
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