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- W3032037735 abstract "Objective To evaluate the efficacy and safety of deep lamellar keratoplasty (DLK) by anhydrous glycerine freezing-preserved corneas for treating fungal keratitis.Methods Thirty-seven (37 eyes) were diagnosed as fungal keratitis,and were not involved Descemet membrane by laser confocal microscopy before surgery.DLK was performed with anhydrous glycerine freezing-preserved cornea.The effectiveness of operation was clinically observed and evaluated,include visual acuity,corneal transparency,topography and endothelium cell density.Results During surgery,four eyes had mini-rupture of the DM and were finished by reserving few deep stroma.Only one eye had a recurrence of the fungal infection within 2 weeks and operated by penetrating keratoplasty (PKP).The best-corrected visual acuity (BCVA) of 22 cases was above 0.5,29 of which were above 0.3 at two weeks after suture removal.The corneal topography astigmatism appeared a decreasing trend,was (4.3±2.2)D,(3.4±2.0)D and (2.1±1.2)D at 1 month,3 months after surgery and 2 weeks after suture removal.There were significant differences (P ＜0.01) in BCVA and corneal topography astigmatism at different time.Mean endothelium cell density was (2396±1219) cells /mm2,(2364±1164) cells /mm2 and (2323±1173) cells /mm2 at 1 month,3 and 12 months after surgery.Two eyes appeared graft edema and became transparent after anti-rejection therapy.Conclusions DLK with anhydrous glycerine freezing-preserved cornea is a safe and effective therapy in the treatment of fungal keratitis not involving Descemet.Key words: Glycerine freezing-preserved; Fungal keratitis; Deep lamellar keratoplasty" @default.
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- W3032037735 date "2014-05-10" @default.
- W3032037735 modified "2023-09-27" @default.
- W3032037735 title "Clinical observation of deep lamellar keratoplasty by Glycerine preserved corneas for treating fungal keratitis" @default.
- W3032037735 doi "https://doi.org/10.3760/cma.j.issn.1006-4443.2014.05.026" @default.
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