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- W3032053824 abstract "ObjectiveTo investigate the expression profil changes of miRNAs in blood of patients with multiple organ dysfunction syndrome (MODS) and discuss their significance.MethodsBlood samples from 3 patients with MODS caused by the lung infection and 3 patients healthy volunteers were used for high-throughput sequencing. A total of 1921 known miRNAs were screened to separate the abnormally expressed miRNAs through the cluster analysis.ResultsThe expression of miR-223 and miR-148a was increased but the expression of miR-1273g was decreased.ConclusionmiR-148a, miR-223 and miR-1273g may play a role in the pathogenesis of MODS, indicating that they are the potential laboratory markers for diagnosis and treatment of MODS.Key words: miRNAs; Multiple organ dysfunction syndrome; Critical care" @default.
- W3032053824 created "2020-06-05" @default.
- W3032053824 creator A5037017467 @default.
- W3032053824 date "2015-08-18" @default.
- W3032053824 modified "2023-09-24" @default.
- W3032053824 title "Expression profile of miRNAs in blood of patients with multiple organ dysfunction syndrome and their implication" @default.
- W3032053824 doi "https://doi.org/10.3877/cma.j.issn.2095-9133.2015.04.007" @default.
- W3032053824 hasPublicationYear "2015" @default.
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