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- W3032056501 abstract "Toll-like receptors (TLR), a family of pattern recognition receptors expressed on mammalian cell surface, are evolutionarily conserved to recognize pathogen-associated molecular patterns. The activation of TLR not only initiates innate immunity, but also regulates enhanced antigen-specific acquired immunity, and thus associates innate and adaptive immunity. Study showed that TLR are host-mediated recognition of Mycobacterium tuberculosis and anti-TB immune response key elements,and that the anti-tuberculosis infection immunity related is mainly TLR2 and TLR4. Research on TLR contributes to a clarification of the pathogenesis of TB and provides the brand-new strategy for its treatment.Key words: Toll-like receptor; Mycobacterium tuberculosis; Innate immunity; Adaptive immunity" @default.
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- W3032056501 date "2009-09-05" @default.
- W3032056501 modified "2023-09-23" @default.
- W3032056501 title "Toll-like receptors and immune roles in anti-tuberculosis infection" @default.
- W3032056501 doi "https://doi.org/10.3760/cma.j.issn.1673-436x.2009.017.008" @default.
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