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- W3032060680 abstract "ObjectiveTo investigate the treatment of elderly dialysis patients with refractory hypertension.MethodsSixty-six patients were randomly divided into two groups of A group and B group, with 33 cases in each group. Patients in A group were treated by routine hemodialysis 3 times per week and hemoperfusion 1 time every 2 weeks. Patients in B group were treated by routine hemodialysis 2 times per week and hemodiafiltration 1 time per week plus hemoperfusion 1 time every 2 weeks. The levels of blood pressure,plasma endothelin (ET), angiotensin-Ⅱ (ATⅡ), renin (RA), parathyroid hormone (PTH) in two groups before and after treatment were compared.ResultsBefore and after treatment, the levels of blood pressure, ET, ATⅡ, RA and PTH in A group were (183.42±16.20)/(109.15±7.69) and (151.45±3.31)/(88.71±4.95) mmHg(1 mmHg=0.133 kPa), (173.45±41.25) and (160.38±25.31) ng/L, (69.21±18.47) and(57.25±23.34) ng/L, (1.21±0.15) and (0.87±0.14) μg/L, (530.27±43.28) and (272.43±34.19) ng/L respectively. Before and after treatment, the levels of blood pressure, ET, ATⅡ, RA and PTH in B group were (185.34±12.26)/(112.38±6.24) and (141.59±4.15)/(80.39±2.73) mmHg, (178.21±34.35) and (149.12±21.34) ng/L,(68.38±23.57) and (47.17±15.61) ng/L, (1.19±0.29) and (0.69±0.41) μg/L, (528.62±42.53) and (253.15±31.62) ng/L respectively. The levels of blood pressure, ET, ATⅡ, RA and PTH in two groups after treatment were significantly decreased compared with those before treatment (P<0.05), and there were significant differences between two groups (P<0.05).ConclusionCombined with hemoperfusion in the treatment of elderly hemodialysis patients with refractory hypertension, the effect of combined hemodiafiltration is significant, and it is worthy of promotion.Key words: Renal dialysis; Hemodiafiltration; Hypertension, renal; Hemoperfusion; Clinical trial" @default.
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- W3032060680 date "2015-07-05" @default.
- W3032060680 modified "2023-09-27" @default.
- W3032060680 title "The therapeutic effect of elderly dialysis patients with refractory hypertension" @default.
- W3032060680 doi "https://doi.org/10.3760/cma.j.issn.1673-4904.2015.07.003" @default.
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