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- W3032081223 abstract "转化生长因子β1是多功能细胞因子,控制细胞生长、分化和细胞外基质沉积,主要参与纤维化,激活成纤维细胞,并能加速创伤愈合,但其过度表达会导致组织器官纤维化.研究表明转化生长因子-β1激活导致信号通路改变,并通过多种机制引发肺上皮-内皮细胞完整性破坏、钠转运失常,导致肺泡液增多和纤维化发生,进而严重影响肺气体交换功能,无论在早期还是晚期急性呼吸窘迫综合征病理发生中均起着非常关键的作用,是急性呼吸窘迫综合征发病的中心环节和分子基础。" @default.
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- W3032081223 date "2008-05-26" @default.
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- W3032081223 title "Progress in research on the relationship between transfroming growth factor-β1 and acute respiratory distress syndrome" @default.
- W3032081223 doi "https://doi.org/10.3760/cma.j.issn.1673-4408.2008.03.013" @default.
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