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- W3032082619 abstract "Objective To investigate the effects of somatostatin combined with total parenteral nutrition(TPN) on malignant bowel obstruction(MBO) due to inoperable gastrointestiinal carcinoma. Methods From Jan. 2003 to Jun. 2008, 29 patients with MBO due inoperable gastrointestinal carcinoma were randomly divided into two groups:the control group(only TPN group) 11 cases and the treatment group(somatostatin combined with TPN) 18 cases(octreotide, 100 μg, subcutaneous injection, tid, for two weeks). The effects were compared between the two groups. Resuits After the treatment, the clinical symptoms of abdominal distention and abdominal pain were relieved significantly (83.33% to 45.45%), the echaust of anus was 66.67% to 27.27%. The average volume of gastroenteral decom-pression reduced more efficiently. Qaality of life, evaluated with Karnofsky score, was improved significantly, the KPS of 88.9% treatment group were higher than 60. Conclusions The administration of somatostatin combined with TPN is effective in the MBO due to inoperable gastrointestinal carcinoma. It can obviously relieve the symptoms of MBO and improve the quality of life in patients.Key words: Somatostatin; Malignant bowel obstruction; Gastrointestinal carcinoma" @default.
- W3032082619 created "2020-06-05" @default.
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- W3032082619 date "2009-11-10" @default.
- W3032082619 modified "2023-09-25" @default.
- W3032082619 title "Effect of somatostatin combined with TPN in malignant bowel obstruction due to inoperable gastrointestinal carci-noma" @default.
- W3032082619 doi "https://doi.org/10.3760/cma.j.issn.1674-4756.2009.21.006" @default.
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