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- W3032098246 abstract "目的 评价肠内营养低聚果糖(FOS)配方在恶性肿瘤患儿中的应用价值和前生物效应.方法 1999年7月至2001年2月,66例2～12岁恶性肿瘤患儿分FOS组(32例)和Non-FOS组(34例)进行前瞻性、随机、双盲对照的临床试验.患儿均按标准方案接受化疗并用Nutren Junior FOS 或Nutren Junior进行30 d的肠内营养支持.分别测定营养支持后第13 d及30 d的身高、体重、血清白蛋白(ALB)和前白蛋白(PA)等营养指标;C反应蛋白(CRP)、肿瘤坏死因子(TNF)等免疫指标,并计算预期感染营养指数;同时测定粪便中双歧杆菌、乳酸杆菌、肠杆菌及产气荚膜梭菌含量.结果两组治疗期间营养和免疫指标的变化无显著差异.但预期感染及营养指数(PINI) D30时FOS组降低更加明显(P=0.016).粪便中双歧杆菌含量在FOS组逐步上升,高于Non-FOS组.FOS组乳酸杆菌含量上升,Non-FOS组变化不明显.结论肠内营养含FOS营养配方可提高抗感染能力、促进肠道正常菌群生长,提示其可能具有前生物效应。" @default.
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- W3032098246 date "2005-01-15" @default.
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- W3032098246 title "The effects of fructo-oligosaccharide in the enteral nutritional support for children with malignant tumors" @default.
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