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- W3032100058 abstract "ObjectiveTo investigate language features of Alzheimer's disease(AD)patients.Methods40 AD patients and 36 healthy controls(HCs)underwent neuropsychological tests(including Mini-Mental State Examination, MMSE), language tests which are revised according to Chinese aphasia battery and Boston naming test(BNT). In order to examine the language impairments of AD in listening, speaking, reading and writing separately, the language was tested by 7 items including auditory comprehension, naming, repetition, reading loudly, speaking, reading comprehension and writing.Cognitive and the language testing results were compared between two groups using a two-sample, two-tailed t-test.The relationship between the scores of MMSE and the performances on language testing in AD was calculated by Pearson correlation.ResultsThe scores in AD group versus healthy controls(HCs)were(441±4)versus(365±126)for auditory comprehension, (161±46)versus(179±2)for repetition, (223±59)vs.(228±6)for naming, (128±46)vs.(158±13)for speaking, (129±51)vs.(149±6)for reading loudly, (154±91)vs.(210±21)for reading comprehension and(8±5)vs.(11±1)for writing, respectively.Compared with the control group, the AD group had significant difference(all P 0.05). Most of the language test performances were not correlated with the MMSE scores(P>0.05), except for reading loudly on sentence and reading comprehension(all P<0.05).ConclusionsThe language damages in AD are manifested mainly with damages in auditory comprehension, naming, speaking, reading comprehension and writing.Language testing is helpful for diagnosing AD.Key words: Alzheimer's disease; Language; Speech" @default.
- W3032100058 created "2020-06-05" @default.
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- W3032100058 date "2016-11-14" @default.
- W3032100058 modified "2023-09-28" @default.
- W3032100058 title "The characteristics of language in Alzheimer's disease patients" @default.
- W3032100058 doi "https://doi.org/10.3760/cma.j.issn.0254-9026.2016.11.003" @default.
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