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- W3032123512 abstract "ObjectiveTo analyze the risk factors of cortical micro-infarcts (CMIs) in patients with acute ischemic stroke and to evaluate the diagnostic value of 3.0 Tesla (T) magnetic resonance imaging (MRI) using double inversion recovery (DIR) sequence and 3-dimensional fluid attenuated inversion recovery (3D-FLAIR) sequence in CMIs in vivo.MethodsOne hundred and ten consecutive patients with acute ischemic stroke within 7 d of onset were chosen from August 2014 to July 2015; these patients were classified into CMIs group and non-CMIs group by results of 3.0 conventional T MRI, DIR-MRI and 3D-FLAIR-MRI. Baseline characteristics and risk factors were analyzed to investigate the independent risk factors of CMIs. The presence of CMIs was evaluated based on conventional T MRI, DIR-MRI and 3D-FLAIR-MRI.ResultsOf the 110 enrolled patients with acute ischemic stroke, CMIs were presented in 23.6% patients(26/110). The age of patients from the CMIs group was significantly older as compared with that of patients from the non-CMIs group (67.65±10.37 vs. 58.52±11.24 years old, P=0.009). Patients from the CMIs group had significantly higher percentages of age>65 years, age of 76-80 years, hypertension, history of cerebral ischemia and intracranial atherosclerosis than patients from non-CMIs group (P 65 years (OR=1.982; 95%CI: 1.362-2.889, P=0.010) and hypertension (OR=1.326; 95%CI: 1.022-1.682, P=0.026) were the independent risk factors of CMIs. The prevalence of CMIs detected by conventional sequence (10.9%) was significantly lower than that detected by DIR sequence (23.6%) or 3D-FLAIR sequence (20.9%, P=0.013 and P=0.043).ConclusionsAge>65 years and hypertension are independent risk factors of CMIs. DIR and 3D-FLAIR sequences at 3.0 T MRI substantially improve the sensitivity of detection of CMIs as compared with conventional MRI sequence.Key words: Cortical micro-infarct; Double inversion recovery; 3-dimensional fluid attenuated inversion recovery; Ischemic stroke" @default.
- W3032123512 created "2020-06-05" @default.
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- W3032123512 date "2017-09-15" @default.
- W3032123512 modified "2023-09-23" @default.
- W3032123512 title "Clinical risk factors and ultrahigh field magnetic resonance imaging features of cerebral microinfarcts" @default.
- W3032123512 doi "https://doi.org/10.3760/cma.j.issn.1671-8925.2017.09.003" @default.
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